2-(1-Methylpiperidin-4-ylidene)acetic acid hydrochloride CAS 676341-72-3
| CAS No. | 676341-72-3 |
| Molecular Formula | C8H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(1-Methylpiperidin-4-ylidene)acetic acid hydrochloride (C8H13NO2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(1-Methylpiperidin-4-ylidene)acetic acid hydrochloride (CAS 676341-72-3), molecular formula C8H13NO2HCl and molecular weight 191.66 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(1-Methylpiperidin-4-ylidene)acetic acid hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H13NO2 HCl |
| Molecular Weight | 191.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methylpiperidin Standards
- 3-(4-Methylpiperidin-1-yl)-4-methylsulfonylaniline (CAS 1000018-37-0)
- 3-(3-Methylpiperidin-1-yl)-4-methylsulfonylaniline (CAS 1000018-39-2)
- 5-(4-Methylpiperidin-1-yl)-2-nitrobenzoic acid (CAS 1000018-43-8)
- 5-(3-Methylpiperidin-1-yl)-2-nitrobenzoic acid (CAS 1000018-45-0)
- 4-[(4-methylpiperidin-1-yl)methyl]benzonitrile (CAS 1000931-95-2)
- (R)-1-Methylpiperidin-3-amine (CAS 1001353-92-9)
- (4-Methylpiperidin-1-yl)(pyrrolidin-2-yl)methanone (CAS 1009747-52-7)
- 4-(4-Methylpiperidin-1-yl)pyrimidine-2-thiol (CAS 1011408-60-8)
Recommended Standards
- 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine-1-carbothioamide (CAS 60782-38-9)
- Methyl 4-(1-methylpiperidin-4-yl)benzoate (CAS 354813-48-2)
- [2-(1H-pyrazol-1-yl)pyridin-3-yl]methylamine (CAS 1052559-31-5)
- (1R*,4R*)-N1-(2-Nitrobenzyl)cyclohexane-1,4-diamine dihydrochloride (CAS 1286274-48-3)
- Testosterone Impurity 67 (CAS 330433-79-9)
- (S)-1-(5-(4-Bromophenyl)-1H-imidazol-2-yl)-2,2-dimethylpropan-1-amine (CAS 1923056-82-9)
- Ethyl 8-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate (CAS 63277-58-7)
- [1,2,3]Thiadiazolo[4,5-c]pyridin-4-amine (CAS 36258-90-9)
- N-(1-benzylpiperidin-4-yl)-3-bromobenzamide (CAS 183158-40-9)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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