6-bromo-4-hydroxy-8-methylquinoline-3-carbonitrile CAS 67643-41-8
| CAS No. | 67643-41-8 |
| Molecular Formula | C11H7BrN2O |
| Molecular Weight | 263.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-bromo-4-hydroxy-8-methylquinoline-3-carbonitrile (C11H7BrN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 6-bromo-4-hydroxy-8-methylquinoline-3-carbonitrile (CAS 67643-41-8), a certified reference material (molecular formula C11H7BrN2O, MW 263.09 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-bromo-4-hydroxy-8-methylquinoline-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H7BrN2O |
| Molecular Weight | 263.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related bromo Standards
- 7-Bromo-2H-pyrazolo[3,4-b]quinolin-3-amine (CAS 1017465-30-3)
- 3-(5-Bromo-1h-indol-3-yl)-3-oxopropanenitrile (CAS 1020722-10-4)
- 4-Bromo-3-cyanoacetylindol (CAS 1171917-27-3)
- 6-Bromo-3-cyanoacetylindol (CAS 1171917-30-8)
- 7-Bromo-3-cyanoacetylindol (CAS 1171917-33-1)
- Ethyl 3-bromo-5-ethoxy-1H-pyrazole-4-carboxylate (CAS 1207431-91-1)
- Ethyl 4-bromo-5-methoxy-1-methyl-1H-pyrazole-3-carboxylate (CAS 1239734-54-3)
- Methyl 3-(4-bromo-1h-pyrazol-1-yl)-2-hydroxy-2-methylpropanoate (CAS 1339895-36-1)
Recommended Standards
- 6-Bromo-[2,2'-bipyridine]-5-carbaldehyde (CAS 605674-25-7)
- 7-bromo-2-hydroxydibenzofuran (CAS 74423-78-2)
- 5-Bromo-3-(1H-imidazol-2-yl)-1H-indazole (CAS 911305-83-4)
- ethyl 5-bromo-2-(2-hydroxyethyl)furan-3-carboxylate (CAS 2044534-89-4)
- 2-Methoxy-4-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1227561-73-0)
- Ethyl 4-(4-chlorophenyl)sulfonylbenzoate (CAS 65082-46-4)
- Levetiracetam Dehydro Acid (CAS 358629-39-7)
- n-[1-(morpholin-4-yl)propan-2-yl]pyrimidin-4-amine (CAS 1249287-43-1)
- 3-(Difluoromethyl)-4-methoxy-5-nitropyridin-2-amine (CAS 1805365-10-9)
- 4-Chloro-5-((3-chlorophenoxy)methyl)-1-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 1024297-59-3)
- 3-(2-Aminophenyl)propanoic acid (CAS 772-21-4)
- 1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium hexafluorophosphate (CAS 135540-11-3)
- N-(2-Benzylphenyl)-2-oxo-1,2-dihydroquinoline-4-carboxamide (CAS 792957-74-5)
- Acetyl Tetrapeptide-5 (CAS 820959-17-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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