tert-Butyl 4-(1H-indol-4-yl)piperidine-1-carboxylate CAS 676448-21-8
| CAS No. | 676448-21-8 |
| Molecular Formula | C18H24N2O2 |
| Molecular Weight | 300.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl 4-(1H-indol-4-yl)piperidine-1-carboxylate (CAS 676448-21-8), molecular formula C18H24N2O2 and molecular weight 300.40 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of tert-Butyl 4-(1H-indol-4-yl)piperidine-1-carboxylate (C18H24N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H24N2O2 |
| Molecular Weight | 300.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl (3-(5-aminonaphthalen-1-yl)propyl)carbamate (CAS 2397550-95-5)
- tert-Butyl 4-(1H-indol-7-yl)piperidine-1-carboxylate (CAS 478083-14-6)
- tert-Butyl (1-amino-1-(naphthalen-2-yl)propan-2-yl)carbamate (CAS 2024284-20-4)
- Tert-butyl 4-benzyl-4-cyanopiperidine-1-carboxylate (CAS 906329-30-4)
- S-Methyl Thioacetate (CAS 1534-08-3)
- β-D-Altropyranose (CAS 7283-10-5)
- Butan-1-aminium tetrafluoroborate (CAS 71852-73-8)
- 1-(Azidomethyl)-3-methylbenzene (CAS 126799-82-4)
- 5-Cyano-1-(2,4-dichlorophenyl)-N-methyl-1H-pyrazole-4-carboxamide (CAS 98475-67-3)
- 10-[(E)-2-{[4-(trifluoromethyl)phenyl]amino}ethenyl]-2,3,7,11-tetraazatricyclo[7.4.0.0^{2,6}]trideca-1(9),3,5,7,10,12-hexaene-5-carbonitrile (CAS 338966-88-4)
- N-((5'-phenyl-[1,1':3',1''-terphenyl]-4'-yl)carbamothioyl)benzamide (CAS 860609-79-6)
- morpholin-3-one hydrazone (CAS 1314994-91-6)
- 2,2-Bis((dodecanoyloxy)methyl)propane-1,3-diyl didodecanoate (CAS 13057-50-6)
- Cycloaspeptide D (CAS 691363-62-9)
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