5-Chloro-1-methyl-1h-1,2,3,4-tetrazole CAS 67648-50-4
| CAS No. | 67648-50-4 |
| Molecular Formula | C2H3ClN4 |
| Molecular Weight | 118.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Chloro-1-methyl-1h-1,2,3,4-tetrazole (CAS 67648-50-4) is a high-purity analytical reference standard with the molecular formula C2H3ClN4 and a molecular weight of 118.53 g/mol.
The molecular framework of 5-Chloro-1-methyl-1h-1,2,3,4-tetrazole (C2H3ClN4) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-Chloro-1-methyl-1h-1,2,3,4-tetrazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C2H3ClN4 |
| Molecular Weight | 118.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 5-Chloro-4H-1,2,4-triazol-3-amine (CAS 130631-49-1)
- 3-Chloro-5-methyl-1,2,4-oxadiazole (CAS 1359822-66-4)
- 2-Chloro-5-methyl-1,3,4-oxadiazole (CAS 98321-75-6)
- 3-chloro-2,5-dihydrofuran-2-one (CAS 31004-27-0)
- 2-Chloro-3-methylcyclopropane-1-carbaldehyde (CAS 139387-00-1)
- 3-Chloro-2-methylbut-2-enal (CAS 1679-40-9)
- 1-Chloro-4-methoxybut-2-yne (CAS 693-27-6)
- 2-Chloro-1-cyclopropylethan-1-one (CAS 7379-14-8)
Recommended Standards
- 5-(Chloromethyl)tetrazole (CAS 55408-11-2)
- Ethyl β-Chlorovinyl Ketone (CAS 105-32-8)
- Methyl-<SUP>13</SUP>C,d<SUB>3</SUB>-sulfonyl chloride (CAS 1216581-01-9)
- Propargyl Chloroformate (CAS 35718-08-2)
- 2-(Difluoromethyl)-5-fluoro-4-iodopyridine-3-carbonyl chloride (CAS 1807135-11-0)
- AG 99 (CAS 122520-85-8)
- 5-(3-Bromobenzyl)-2-morpholinothiazol-4-amine (CAS 1387573-85-4)
- 4-Chloropyrazole-1-acetic Acid (CAS 32089-46-6)
- 4-(3-IODO-1H-PYRAZOL-4-YL)PYRIMIDINE (CAS 1111638-50-6)
- 5-methoxypyrazolo[1,5-a]pyridine-2,3-dicarboxylic acid (CAS 2752903-99-2)
- Methotrexate Impurity 72 (CAS CATO-C4X-115472)
- 4-Amino-6-fluoroquinoline-3-carbohydrazide (CAS 1018127-71-3)
- 1-(4-fluorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline (CAS 55507-14-7)
- Hexapeptide-9 (CAS 885024-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com