N,N,N-Trimethyl-2-phenylquinazolin-4-aminium chloride CAS 67824-27-5

Purity 97%+In StockPharmaceutical Standards
CAS No.67824-27-5
Molecular FormulaC17H18N3
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N,N,N-Trimethyl-2-phenylquinazolin-4-aminium chloride CAS 67824-27-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N,N,N-Trimethyl-2-phenylquinazolin-4-aminium chloride.

N,N,N-Trimethyl-2-phenylquinazolin-4-aminium chloride (CAS 67824-27-5), molecular formula C17H18N3Cl and molecular weight 299.80 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N,N,N-Trimethyl-2-phenylquinazolin-4-aminium chloride (C17H18N3Cl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N,N,N-Trimethyl-2-phenylquinazolin-4-aminium chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H18N3 Cl
Molecular Weight299.80 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1976
Halogen ContentCl-containing
Nitrogen Atoms3

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