2,2,6,6-Tetramethylpiperidine-4-carbonitrile CAS 67845-90-3
| CAS No. | 67845-90-3 |
| Molecular Formula | C10H18N2 |
| Molecular Weight | 166.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,2,6,6-Tetramethylpiperidine-4-carbonitrile (C10H18N2) is characterized by a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2,2,6,6-Tetramethylpiperidine-4-carbonitrile (CAS 67845-90-3) is a high-purity analytical reference standard with the molecular formula C10H18N2 and a molecular weight of 166.26 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,2,6,6-Tetramethylpiperidine-4-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H18N2 |
| Molecular Weight | 166.26 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 2 |
Related Tetramethylpiperidine Standards
- 2,2,6,6-Tetramethylpiperidine-4-carbaldehyde (CAS 53085-38-4)
- 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-1-15N-1-OXYL 33490-11-8 (CAS 33490-11-8)
- 4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical (CAS 2896-70-0)
- 4-Oxo-2,2,6,6-tetramethylpiperidine-d17 (CAS 52168-48-6)
- 2,2,6,6-tetramethylpiperidine-1,4-diol (CAS 3637-10-3)
- 2,2,6,6-Tetramethylpiperidine-d18-1-oxyl (CAS 205679-68-1)
- 2,2,6,6-Tetramethylpiperidine 1-Oxyl Free Radical (CAS 2564-83-2)
- 2,2,6,6-Tetramethylpiperidine-4-carboxamide (CAS 325691-90-5)
Recommended Standards
- 2-(3,3-Dimethylbutan-2-yl)-1-methyl-1H-imidazole (CAS 746624-20-4)
- 2,2-Dimethyl-1-(1-methyl-1H-pyrrol-2-yl)propan-1-amine (CAS 654683-82-6)
- 2-(2-Butyl-1H-pyrrol-1-yl)ethanamine (CAS 499200-69-0)
- 2,3-Bis(1,1-dimethylethyl)-2-cyclopropen-1-one (CAS 19985-79-6)
- 2-Chloro-N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)benzamide (CAS 338784-47-7)
- 4-(Benzyloxy)-3-fluorobenzaldehyde (CAS 175968-61-3)
- (3-((Furan-2-ylmethyl)sulfonyl)pyrrolidin-1-yl)(furan-3-yl)methanone (CAS 1795303-89-7)
- 1-(2,2,2-Trifluoroacetyl)-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride (CAS 947498-97-7)
- tert-Butyl 1',2'-dihydrospiro[piperidine-4,3'-pyrrolo[2,3-b]pyridine]-1-carboxylate (CAS 857730-07-5)
- Methyl 3-bromo-1H-indazole-6-carboxylate (CAS 192945-56-5)
- 2-Cyclohexyl-2-(2-(4-fluorophenyl)-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)ethanol (CAS 1363405-55-3)
- Naltrexone impurity 40 (CAS CATO-C4X-147540)
- 2-Ethyl-4-(4-methylthiazol-2-yl)thieno[3,2-d]pyrimidine (CAS 443148-31-0)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
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