3-Chloro-5-(2-methoxyphenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine CAS 678560-80-0
| CAS No. | 678560-80-0 |
| Molecular Formula | C15H11ClF3N3O |
| Molecular Weight | 341.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Chloro-5-(2-methoxyphenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 678560-80-0), a certified reference material (molecular formula C15H11ClF3N3O, MW 341.72 g/mol) for analytical method development and quality control.
The molecular framework of 3-Chloro-5-(2-methoxyphenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (C15H11ClF3N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Chloro-5-(2-methoxyphenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11ClF3N3O |
| Molecular Weight | 341.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-5-(3-methoxyphenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 740837-57-4)
- 3-Chloro-5-(4-methoxyphenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 677345-89-0)
- 5-(2-Chloro-4-(trifluoromethyl)phenoxy)-3-ethylbenzo[d]isoxazole (CAS 114195-16-3)
- 2-(4-Chloro-2-methylphenoxy)-2,2-difluoro-N-(4-methoxyphenyl)acetamide (CAS 339010-99-0)
- 2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(2-thienylmethyl)malononitrile (CAS 339102-34-0)
- 4-(2-Chloro-4-nitrostyryl)benzene-1-sulfonyl fluoride (CAS 21278-66-0)
- 4-(2-Chloro-5-nitrostyryl)benzene-1-sulfonyl fluoride (CAS 31368-33-9)
- 4-Chloro-5,7-bis(4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 907585-57-3)
Recommended Standards
- 2-[(4-Chlorophenyl)sulfonyl]-5-nitrobenzoic acid (CAS 99768-25-9)
- Diiodo(phenyl)borane (CAS 17381-60-1)
- 3-(3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl)-6-fluoroquinolin-4(1H)-one (CAS 1081119-02-9)
- 2-(tert-Butyl)-6-(trifluoromethyl)benzo[d]oxazole-7-sulfonyl chloride (CAS 914638-38-3)
- 2-((1-(Cyclopropylmethyl)-1H-indol-3-yl)thio)acetonitrile (CAS 61021-42-9)
- (R)-3-amino-4-(4-bromophenyl)butanoic acid (CAS 773045-17-3)
- 1-Cyclopropyl-N-((2-methoxypyridin-3-yl)methyl)ethan-1-amine (CAS 1178934-78-5)
- 2-Chloro-5-methylpyrimidine (CAS 22536-61-4)
- Methotrexate Triglutamate (CAS 41600-14-0)
- 1-(5-Chlorobenzo[d]oxazol-2-yl)-N-methylmethanamine (CAS 1017782-51-2)
- (E)-3-(2-methoxy-5-nitrophenyl)-2-propenoic acid (CAS 288151-91-7)
- 6-Chloro-5-phenylpyrazin-2-amine (CAS 1357159-12-6)
- ethyl 4-chlorothieno[2,3-d]pyrimidine-2-carboxylate (CAS 1192540-11-6)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com