Ethyl 5-(1-naphthyl)-7-(trifluoromethyl)pyrazolo-[1,5-a]pyrimidine-3-carboxylate CAS 679830-65-0
| CAS No. | 679830-65-0 |
| Molecular Formula | C20H14F3N3O2 |
| Molecular Weight | 385.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ethyl 5-(1-naphthyl)-7-(trifluoromethyl)pyrazolo-[1,5-a]pyrimidine-3-carboxylate (CAS 679830-65-0), a certified reference material (molecular formula C20H14F3N3O2, MW 385.34 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 5-(1-naphthyl)-7-(trifluoromethyl)pyrazolo-[1,5-a]pyrimidine-3-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 385.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H14F3N3O2 |
| Molecular Weight | 385.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- N-(1-naphthyl)-N-(9-phenylcarbazol-3-yl)amine (CAS 894791-44-7)
- 2,3-Di(2-naphthyl)quinoxaline (CAS 193699-26-2)
- 1-(2-Naphthyl)-1-ethanone N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]hydrazone (CAS 36941-40-9)
- N-[4-(1-Naphthyl)phenyl]-4-biphenylamine (CAS 897921-59-4)
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- 2-Naphthyl[6-(2-naphthyl)-3-pyridinyl]methanone (CAS 502841-00-1)
- 1-Naphthyl 2-(6-Methoxy-2-naphthyl)propanoate (CAS 1385694-62-1)
- 2-Naphthyl Myristate (CAS 7262-80-8)
Recommended Standards
- Ethyl 1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 385416-12-6)
- Ethyl 5-(naphthalen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 352216-57-0)
- Ethyl 1-[4-(3-fluorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 385416-11-5)
- Macrozamin (CAS 6327-93-1)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with butyl 2-propenoate and ethyl 2-propenoate (CAS 25767-43-5)
- 2-[(4-methylphenyl)methoxy]acetic acid (CAS 51934-40-8)
- 1-[(3S)-3-Aminopyrrolidin-1-yl]propan-1-one (CAS 1286317-67-6)
- Brassicasterol Impurity 1 (Brassicasterol 3-OAC) (CAS 2458-53-9)
- 1-Cyclopropoxy-3-fluoro-2-isopropoxybenzene (CAS 1243391-75-4)
- (S)-1-(3-bromo-5-fluorophenyl)ethan-1-amine (CAS 1241677-61-1)
- 2-(2,4-Dimethylphenoxy)-1-(piperazin-1-yl)propan-1-one (CAS 1017025-32-9)
- 1,2-Dichlorocyclohexane (CAS 1121-21-7)
- 1-((2,6-Dichlorophenyl)sulfonyl)piperazine (CAS 900641-41-0)
- C-Peptide 2 (rat) (CAS 41594-08-5)
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