diethyl [4-(trifluoromethyl)benzoyl]phosphonate CAS 680215-36-5
| CAS No. | 680215-36-5 |
| Molecular Formula | C12H14F3O4P |
| Molecular Weight | 310.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including diethyl [4-(trifluoromethyl)benzoyl]phosphonate.
CATO supplies diethyl [4-(trifluoromethyl)benzoyl]phosphonate (CAS 680215-36-5), a certified reference material (molecular formula C12H14F3O4P, MW 310.21 g/mol) for analytical method development and quality control.
diethyl [4-(trifluoromethyl)benzoyl]phosphonate (C12H14F3O4P) contains a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14F3O4P |
| Molecular Weight | 310.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related diethyl Standards
- diethyl [3-(trifluoromethyl)benzoyl]phosphonate (CAS 86208-45-9)
- Diethyl (fluoro(phenylsulfonyl)methyl)phosphonate (CAS 114968-97-7)
- Diethyl 2,2-(1,3-Dithietane-2,4-diylidene)bis(cyanoacetate) (CAS 22624-54-0)
- Diethyl 6-methyl-4-oxo-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidine-1,3(4H,6H)-dicarboxylate (CAS 33499-13-7)
- trans-Diethyl Stilbestrol Acetate (CAS 66320-32-9)
- 4-(2,6-Diethyl-phenyl)-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol (CAS 380442-83-1)
- diethyl 2-(((benzyloxy)carbonyl)amino)malonate (CAS 3005-66-1)
- diethyl 2-(2-nitro-1-phenylethyl)malonate (CAS 22975-21-9)
Recommended Standards
- n-(2-Bromo-4-methylphenyl)-2-(thiophen-3-yl)acetamide (CAS 850601-61-5)
- 4,4'-Oxybis(isobenzofuran-1,3-dione) (CAS 50662-96-9)
- n-(4-Bromo-3-methylphenyl)-2-(thiophen-3-yl)acetamide (CAS 727716-78-1)
- 4-(4-Bromophenyl)-2-(2-(propan-2-ylidene)hydrazinyl)thiazole (CAS 324065-65-8)
- 2-Methyl-N-(1-methyl-1H-pyrazol-3-yl)butanamide (CAS 1171799-58-8)
- Ethyl 2-Fluorobenzoylformate (CAS 1813-93-0)
- Sodium 2-(4-nitrophenyl)acetate (CAS 7063-24-3)
- tert-Butyl 9-amino-3-azaspiro[5.5]undecane-3-carboxylate (CAS 1272758-41-4)
- (6-(Difluoromethyl)pyridin-3-yl)boronic acid (CAS 2407646-08-4)
- (Gly21)-Amyloid β-Protein (1-40) trifluoroacetate salt (CAS 154362-03-5)
- 2-(2-Chlorobenzo[d]oxazol-7-yl)acetonitrile (CAS 1803838-05-2)
- Cefazolin EP Impurity K (CAS 2410652-70-7)
- 2-{[(4-chlorophenyl)methyl]sulfanyl}-1-[4-(trifluoromethyl)benzoyl]-1,4,5,6-tetrahydropyrimidine (CAS 866153-37-9)
- [γ-Glu]15 Semaglutide (CAS CATO-C4X-222690)
Why CATO?
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