N3-imino[4-(trifluoromethyl)phenyl]methyl-2,5-dichloronicotinamide CAS 680216-89-1
| CAS No. | 680216-89-1 |
| Molecular Formula | C14H8Cl2F3N3O |
| Molecular Weight | 362.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N3-imino[4-(trifluoromethyl)phenyl]methyl-2,5-dichloronicotinamide.
N3-imino[4-(trifluoromethyl)phenyl]methyl-2,5-dichloronicotinamide (CAS 680216-89-1), molecular formula C14H8Cl2F3N3O and molecular weight 362.13 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N3-imino[4-(trifluoromethyl)phenyl]methyl-2,5-dichloronicotinamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 362.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N3-imino[4-(trifluoromethyl)phenyl]methyl-2,5-dichloronicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl2F3N3O |
| Molecular Weight | 362.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- Methyl 2-imino-5-oxo-1-(pyridin-3-ylmethyl)-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate (CAS 510761-44-1)
- 2-Imino-N-methyl-5-oxo-1-(pyridin-3-ylmethyl)-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide (CAS 510761-47-4)
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Recommended Standards
- N1-[(2,6-dichloro-4-pyridyl)(imino)methyl]-3-(trifluoromethyl)benzamide (CAS 266337-66-0)
- 2-(tri-n-butyltinyl)oxazole (CAS 145214-05-7)
- Methyl 2-bromo-7-nitro-9-oxo-9H-fluorene-4-carboxylate (CAS 887575-62-4)
- 2-(2H-1,3-Benzodioxol-5-yl)-3-bromo-6-nitroimidazo[1,2-a]pyridine (CAS 904814-03-5)
- Glucodigifucoside (CAS 2446-63-1)
- 3-(Chloromethyl)-3-isobutyltetrahydro-2h-pyran (CAS 1696978-64-9)
- 2-Amino-3-cyclopropoxy-N,N-dimethylisonicotinamide (CAS 1243320-24-2)
- 4,5-Dibromo-2,3-difluorotoluene (CAS 1803783-79-0)
- 2-Methyl-4,5-dihydro-1,3,4-benzoxadiazepin-5-one (CAS 144760-62-3)
- 1-{5-[(propan-2-yloxy)methyl]-1,2,4-oxadiazol-3-yl}ethan-1-amine (CAS 1566973-20-3)
- (5Z)-5-{[(3,4-dichlorophenyl)amino]methylidene}-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrol-2-one (CAS 339012-09-8)
- 5-Amino-N-(3-methoxyphenyl)-1-phenethyl-1H-1,2,3-triazole-4-carboxamide (CAS 909856-88-8)
- Stachyose Tetrahydrate (CAS 10094-58-3)
- Protein Kinase C? Peptide Substrate (CAS 120253-69-2)
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