2,6-Dichloro-5-fluoro-N-(thiophen-2-ylmethyl)nicotinamide CAS 680217-82-7
| CAS No. | 680217-82-7 |
| Molecular Formula | C11H7Cl2FN2OS |
| Molecular Weight | 305.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,6-Dichloro-5-fluoro-N-(thiophen-2-ylmethyl)nicotinamide (CAS 680217-82-7), a certified reference material (molecular formula C11H7Cl2FN2OS, MW 305.16 g/mol) for analytical method development and quality control.
Structurally, 2,6-Dichloro-5-fluoro-N-(thiophen-2-ylmethyl)nicotinamide (C11H7Cl2FN2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 305.16 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,6-Dichloro-5-fluoro-N-(thiophen-2-ylmethyl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7Cl2FN2OS |
| Molecular Weight | 305.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichloro Standards
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Recommended Standards
- 2,6-Dichlorobenzene-1,4-disulfonamide (CAS 19986-78-8)
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- 2-(Chloromethyl)-3-(4-chlorophenyl)quinazolin-4(3H)-one (CAS 22280-87-1)
- 3-Benzyl-7-(phenylsulfonyl)-9-oxa-3,7-diazabicyclo[3.3.1]nonane (CAS 335620-96-7)
- Ethyl 4-(N-(2-chlorobenzyl)methylsulfonamido)benzoate (CAS 592472-65-6)
- 4-Hydroxy-2-(trifluoromethoxy)benzonitrile (CAS 1261648-89-8)
- 2-Benzyl 1-(tert-butyl) (2S,4R)-4-(4-bromobenzyl)-5-oxopyrrolidine-1,2-dicarboxylate (CAS 401793-01-9)
- (S)-2-Amino-3-(1H-imidazol-5-yl)propanoic acid compound with acetic acid (1:1) (CAS 71173-63-2)
- tert-Butyl 6-formyl-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine-2-carboxylate (CAS 1174068-79-1)
- PCB No. 97 (CAS 41465-51-1)
- (5-Methoxy-3-(trifluoromethyl)pyridin-2-yl)methanol (CAS 1804438-77-4)
- 4-(chloromethyl)-2-(2,6-dichlorophenyl)-1,3-thiaZole (CAS 90877-03-5)
- (Leu31,Pro3?)-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 132699-73-1)
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