2,6-Dichloro-5-fluoro-N-(pyridin-3-yl)nicotinamide CAS 680217-89-4

Description

Compared with other compounds in its class, the molecular weight of 286.09 g/mol gives 2,6-Dichloro-5-fluoro-N-(pyridin-3-yl)nicotinamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2,6-Dichloro-5-fluoro-N-(pyridin-3-yl)nicotinamide (CAS 680217-89-4), molecular formula C11H6Cl2FN3O and molecular weight 286.09 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2,6-Dichloro-5-fluoro-N-(pyridin-3-yl)nicotinamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 286.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,6-Dichloro-5-fluoro-N-(pyridin-3-yl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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