4-(1-(2,5-Difluorophenyl)-6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol CAS 680610-84-8
| CAS No. | 680610-84-8 |
| Molecular Formula | C19H12F2N2O3 |
| Molecular Weight | 354.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(1-(2,5-Difluorophenyl)-6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol.
4-(1-(2,5-Difluorophenyl)-6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol (CAS 680610-84-8), molecular formula C19H12F2N2O3 and molecular weight 354.31 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C19H12F2N2O3, 4-(1-(2,5-Difluorophenyl)-6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 354.31 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(1-(2,5-Difluorophenyl)-6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H12F2N2O3 |
| Molecular Weight | 354.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- (2,5-Difluorophenyl)(2-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)methanone (CAS 1413527-61-3)
- 2-(2,6-Difluorophenyl)-1-[(2,6-Difluorophenyl)Methyl]Benzimidazole (CAS 199594-59-7)
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Recommended Standards
- 3,4-Bis(4-methoxybenzoyl)-1,2,5-oxadiazole 2-oxide (CAS 40499-78-3)
- 4-(2-(3-Nitrophenoxy)acetamido)benzene-1-sulfonyl fluoride (CAS 30885-87-1)
- 3-(Piperidinomethyl)-2-Norbornanone (CAS 71172-60-6)
- 4-(2-(4-Nitrophenoxy)acetamido)benzene-1-sulfonyl fluoride (CAS 21315-95-7)
- 19955-99-8 3-Vinylbenzaldehyde DTXSID20275415 (CAS 19955-99-8)
- tert-Butyl (1R)-1-((tert-butylsulfinyl)amino)-8-azaspiro[4.5]decane-8-carboxylate (CAS 2055761-18-5)
- Tributylphosphonium tetrafluoroborate (CAS 113978-91-9)
- 4-((4-Acetamidophenyl)amino)-4-oxobut-2-enoic acid (CAS 108749-44-6)
- Cefixime Impurity 100 (CAS CATO-C4X-1139100)
- Deltorphin (CAS 119975-64-3)
- 5-Bromo-2-cyclopropyl-3-methoxypyridine (CAS 1241752-52-2)
- [1-(3,4-Dichlorophenyl)-1H-1,2,3-triazol-4-yl]methyl 2,4-dichlorobenzoate (CAS 338419-41-3)
- 1,4-Hexadien-3-ol (CAS 1070-14-0)
- D-Ser39-Tirzepatide (CAS CATO-CPTD788679)
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