4-chloro-6-nitroquinazolin-7-amine CAS 680972-68-3
| CAS No. | 680972-68-3 |
| Molecular Formula | C8H15ClN4O2 |
| Molecular Weight | 234.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-chloro-6-nitroquinazolin-7-amine is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-chloro-6-nitroquinazolin-7-amine (CAS 680972-68-3), molecular formula C8H15ClN4O2 and molecular weight 234.68 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-chloro-6-nitroquinazolin-7-amine (C8H15ClN4O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 234.68 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-chloro-6-nitroquinazolin-7-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H15ClN4O2 |
| Molecular Weight | 234.68 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
- 2-chloro-N-quinolin-5-ylpropanamide (CAS 1000930-68-6)
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- 5-Chloro-3-ethyl-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 1046784-61-5)
- 4-Chloro-6-(2-ethoxyphenyl)pyrimidine (CAS 1073485-22-9)
- 1098347-54-6 2-Chloro-N-quinolin-3-ylpropanamide MFCD11644441 (CAS 1098347-54-6)
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Recommended Standards
- 4-Chloro-6-methyl-5-(phenylmethoxy)pyrimidine (CAS 2869955-50-8)
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- 4-Chloro-6-(4-ethoxyphenyl)pyrimidine (CAS 954224-15-8)
- 5-(2-Chlorostyryl)-3-methylisoxazol-4-amine (CAS 53558-05-7)
- 2-Isoproxy-3-methylpyridine-5-boronic acid pinacol ester (CAS 1375303-04-0)
- 1-(3-Fluorophenyl)-2-thiourea (CAS 458-05-9)
- [4-(Aminomethyl)-1,2-dimethyl-5-phenyl-2-pyrrolidinyl]methanol (CAS 1052611-74-1)
- 2-(4-Methoxy-3-(methylsulfonyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 918328-09-3)
- (3R,3aS,6R,6aS)-Hexahydrofuro[3,2-b]furan-3,6-diamine (CAS 143396-58-1)
- methyl 9-oxo-6,9-dihydro-7H-pyrano[4,3-e][1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylate (CAS 1087792-34-4)
- Ethyl 2-(2-Methoxyethyl)oxazole-4-carboxylate (CAS 2070896-70-5)
- N-(2-(Imidazo[1,2-a]pyridin-2-yl)ethyl)-4-methylbenzenesulfonamide (CAS 868978-63-6)
- 1-(Methoxymethyl)-2-prop-2-enoxybenzene (CAS 110731-13-0)
- DAPK Substrate Peptide (CAS 386769-53-5)
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