N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-2-((2-(3-methylpiperidin-1-yl)-2-oxoethyl)thio)acetamide CAS 681224-96-4
| CAS No. | 681224-96-4 |
| Molecular Formula | C17H20ClN3O2S3 |
| Molecular Weight | 430.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-2-((2-(3-methylpiperidin-1-yl)-2-oxoethyl)thio)acetamide.
CATO supplies N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-2-((2-(3-methylpiperidin-1-yl)-2-oxoethyl)thio)acetamide (CAS 681224-96-4), a certified reference material (molecular formula C17H20ClN3O2S3, MW 430.01 g/mol) for analytical method development and quality control.
Structurally, N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-2-((2-(3-methylpiperidin-1-yl)-2-oxoethyl)thio)acetamide (C17H20ClN3O2S3) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 430.01 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H20ClN3O2S3 |
| Molecular Weight | 430.01 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 3 |
Related N Standards
- N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-2-((2-(2-methylpiperidin-1-yl)-2-oxoethyl)thio)acetamide (CAS 681224-95-3)
- 5-(1-((5-Chlorothiophen-2-yl)sulfonyl)azetidin-3-yl)-3-(2-methoxybenzyl)-1,2,4-oxadiazole (CAS 1396792-62-3)
- 1-((5-Chlorothiophen-2-yl)sulfonyl)-4-((4-fluorophenyl)sulfonyl)piperidine (CAS 1448128-43-5)
- 5-(5-Chlorothiophen-2-yl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-3-carbohydrazide (CAS 303106-96-9)
- Ethyl 5-(3-chlorothiophen-2-yl)-2-(4-(4-methoxyphenyl)piperazin-1-yl)-1H-pyrrole-3-carboxylate (CAS 477845-25-3)
- N-(5-((5-Chlorothiophen-2-yl)sulfonyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)thiophene-2-carboxamide (CAS 1351587-52-4)
- 1-(3-Chlorothiophen-2-yl)-2-((5-(4-pentylcyclohexyl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one (CAS 860611-05-8)
- Ethyl 1-(4-(5-chlorothiophen-2-yl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 956781-14-9)
Recommended Standards
- 9,10-Diiodoanthracene (CAS 113705-11-6)
- 2-(Allylthio)-4-((4-chlorophenyl)thio)-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidine (CAS 672950-76-4)
- 6-Bromo-3-iodo-2-(2H-tetrazol-5-yl)benzenesulfonamide (CAS 1802371-06-7)
- 2,7-Dibromo-1,4,5,8-tetrahydroxyanthracene-9,10-dione (CAS 88318-13-2)
- 3-(2-Methoxy-2-oxoethoxy)benzoic acid (CAS 113496-13-2)
- CAS 635678-86-3 (CAS 635678-86-3)
- 4-Ethyl-1H-pyrazol-3-amine oxalate (CAS 1010800-27-7)
- 6-(Difluoromethyl)isoquinoline (CAS 1204298-75-8)
- TERT-BUTYL 3-(N-BENZYL-N-METHYLAMINO) PIPERIDINE-1-CARBOXYLATE (CAS 1027345-51-2)
- 2-Hydroxypyrene-1-carbaldehyde (CAS 96918-22-8)
- (1-((8-Oxa-5-azaspiro[3.5]nonan-5-yl)methyl)cyclopropyl)methanol (CAS 2771460-01-4)
- 6-Bromo-N-methylpyridin-3-amine (CAS 1022641-52-6)
- 1-tert-Butyl 7-methyl 2-nitro-1H-indole-1,7-dicarboxylate (CAS 1881332-51-9)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
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