(R)-4,4'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol CAS 681481-94-7
| CAS No. | 681481-94-7 |
| Molecular Formula | C17H14Br2O2 |
| Molecular Weight | 410.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (R)-4,4'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol is closely related to a steroid core, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (R)-4,4'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol (CAS 681481-94-7), a certified reference material (molecular formula C17H14Br2O2, MW 410.10 g/mol) for analytical method development and quality control.
Owing to a steroid core, a hydroxyl group, an ether linkage, bromine substitution, (R)-4,4'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 410.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (R)-4,4'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H14Br2O2 |
| Molecular Weight | 410.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Br-containing |
Related R Standards
- (R)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol (CAS 1286189-15-8)
- (S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol (CAS 1621066-74-7)
- 6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol (CAS 1807777-59-8)
- (S)-4,4'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol (CAS 636601-27-9)
- 4,4'-Dibromo-1,1'-spirobiindane-7,7'-diol (CAS 681481-91-4)
- 8,10-Dibromo-5,6-dihydro-2,4-dimethyl-4H-benzo[b]furo[3′,2′:6,7]cyclohepta[1,2-d]furan (CAS 220542-74-5)
- 2,2'-((2,5-Dibromo-1,4-phenylene)bis(oxy))bis(N,N-diethylethan-1-amine) (CAS 233753-19-0)
- (3,4-Dibromo-3,4,4-trifluorobutanesulfonyl)benzene (CAS 478247-75-5)
Recommended Standards
- 3,10-Dibromoperylene (CAS 85514-20-1)
- 3,9-Dibromoperylene (CAS 56752-35-3)
- 1,4-BIs(1h-naphtho[1,8-de][1,3,2]diazaborinin-2(3h)-yl)benzene (CAS 1254172-22-9)
- 3-(2,2-Dichlorovinyl)-N-(4-iodophenyl)-2,2-dimethylcyclopropane-1-carboxamide (CAS 301359-13-7)
- Ethyl 4-oxo-1-phenoxy-4H-quinolizine-3-carboxylate (CAS 101192-59-0)
- Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate (CAS 40106-13-6)
- N-((1-(2-Chloroacetyl)pyrrolidin-3-yl)methyl)-N-isopropylacetamide (CAS 1353958-10-7)
- Vonoprazan Impurity 205 (CAS CATO-C4X-1020205)
- Salbutamol Impurity 141 (CAS CATO-C4X-1176141)
- Methyl 8-chloroisoquinoline-3-carboxylate (CAS 1823314-55-1)
- 5-(tert-Butyl)-3-(dibenzo[b,d]furan-4-yl)-2-hydroxybenzaldehyde (CAS 402576-63-0)
- 1-Cyclopropyl-6,7-difluoro-1,2,3,4-tetrahydroquinolin-4-amine (CAS 1038842-61-3)
- 1-(1h-Indazole-6-carbonyl)piperidin-4-ol (CAS 1155926-98-9)
- Des-Gly29,30-Tirzepatide (CAS CATO-CPTD788944)
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