(βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate CAS 681490-92-6
| CAS No. | 681490-92-6 |
| Molecular Formula | C8H12ClN3O6S |
| Molecular Weight | 313.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate (CAS 681490-92-6), molecular formula C8H12ClN3O6S and molecular weight 313.72 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate (C8H12ClN3O6S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12ClN3O6S |
| Molecular Weight | 313.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related R Standards
- 2-(6-Chloro-4-trifluoromethyl-pyridin-2-ylsulfanyl)-propionic acid ethyl ester (CAS 1858255-94-3)
- 2-Chloro-5-nitro-N-(pyridin-3-yl)benzenesulfonamide (CAS 330189-04-3)
- 1-{4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl}-3-(2,2-difluoroethyl)-3-methylazetidine (CAS 2809808-30-6)
- 2-Chloro-1-{1-[4-(difluoromethoxy)phenyl]-2,5-dimethyl-1h-pyrrol-3-yl}ethan-1-one (CAS 725710-57-6)
- 5-(2-Chloro-4-fluorobenzamido)-3-methylthiophene-2-carboxylic acid (CAS 926235-15-6)
- 2-(2-Chloro-4-fluoro-5-(5-hydroxy-1-methyl-1H-pyrazol-3-yl)phenoxy)-N-methylacetamide (CAS 2151826-99-0)
- Methyl 3-(2-chloro-6-nitrophenoxy)thiophene-2-carboxylate (CAS 91041-19-9)
- 6-Chloro-2-(4-methoxyphenyl)quinoline-4-carboxylic acid (CAS 116734-25-9)
Recommended Standards
- (2-Chlorothiazol-5-yl)methyl (4-nitrophenyl)carbamate (CAS 672949-95-0)
- ({5-[(4-Chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl}amino)(oxo)acetic acid (CAS 931374-35-5)
- Phenyl (6-chloropyridazin-3-yl)sulfonylcarbamate (CAS 89391-74-2)
- 4-[(4-fluorobenzene)amido]benzene-1-sulfonyl chloride (CAS 1016713-31-7)
- N-tert-Butyl-3,5-dimethyl-1H-pyrazole-4-sulfonamide (CAS 1032038-96-2)
- N-benzyl-5-bromo-N-ethyl-3-methylpyridin-2-amine (CAS 1219971-97-7)
- Methyl 5-Bromo-2-furoate (CAS 2527-99-3)
- 1-2-3-4-6-Penta-O-acetyl-α-D-glucopyranose (CAS 604-68-2)
- 1,3-Bis((tert-butyldimethylsilyl)oxy)benzene (CAS 120951-86-2)
- 1-(4-tert-butyl-1,3-thiazol-2-yl)ethan-1-amine (CAS 642931-77-9)
- 2-(2-Ethylthiazol-4-yl)acetic acid (CAS 933732-31-1)
- 2-(4-Chlorophenyl)-4-(hydroxymethylene)oxazol-5(4H)-one (CAS 209742-75-6)
- 4-Methoxy-n-(piperidin-4-yl)pyrimidin-2-amine (CAS 1156837-11-4)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com