1-(4-Methylbenzoyl)piperidine-2-carboxylic acid CAS 681827-45-2
| CAS No. | 681827-45-2 |
| Molecular Formula | C14H17NO3 |
| Molecular Weight | 247.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 247.29 g/mol gives 1-(4-Methylbenzoyl)piperidine-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(4-Methylbenzoyl)piperidine-2-carboxylic acid (CAS 681827-45-2), molecular formula C14H17NO3 and molecular weight 247.29 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-(4-Methylbenzoyl)piperidine-2-carboxylic acid (C14H17NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 247.29 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H17NO3 |
| Molecular Weight | 247.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
Related Methylbenzoyl Standards
- 1-(2-Methylbenzoyl)piperidine-2-carboxylic acid (CAS 1101227-14-8)
- 1-(3-Methylbenzoyl)piperidine-2-carboxylic acid (CAS 1102896-88-7)
- 4-(2-Methylbenzoyl)isoquinoline (CAS 1187166-17-1)
- Methyl (3-methylbenzoyl)-D-prolinate (CAS 1354970-52-7)
- 4-(3-Methylbenzoyl)quinoline (CAS 1706436-11-4)
- 4-(4-Methylbenzoyl)quinoline (CAS 1706456-62-3)
- 1-(2-Methylbenzoyl)piperidine-3-carboxylic acid (CAS 926247-53-2)
- 1-(2-Methylbenzoyl)piperidine-4-carboxylic acid (CAS 401581-31-5)
Recommended Standards
- 1-(4-Ethylbenzyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 824981-40-0)
- 1-(4-Methylbenzoyl)piperidine-4-carboxylic acid (CAS 401581-34-8)
- 1-(4-Acetylphenyl)piperidine-4-carboxylic acid (CAS 250713-76-9)
- 1-(5-((2-Hydroxyethyl)thio)-4-nitrothiophen-2-yl)ethan-1-one (CAS 845266-22-0)
- Netupitant (CAS 290297-26-6)
- 2-(3-Aminopropyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one Hydrochloride (CAS 1193388-32-7)
- (S)-2-(Pyridin-3-yl)pyrrolidine-1-carbaldehyde (CAS 38840-03-8)
- 1-(Fluoromethyl)-3-methylbenzene (CAS 456-44-0)
- tert-butyl 4-(bromomethyl)-3,3-difluoropiperidine-1-carboxylate (CAS 1303974-03-9)
- 1-(2-Bromoethoxy)-4-fluorobenzene (CAS 332-48-9)
- 1-Benzyl-2-phenyl-1H-imidazole (CAS 37734-89-7)
- 4-Chloro-N-(pyrrolidin-2-ylmethyl)aniline dioxalate (CAS 1177340-80-5)
- (E)-3-(2-(difluoromethoxy)-5-nitrophenyl)acrylic acid (CAS 327105-74-8)
- Tirzepatide Impurity 58 (CAS CATO-C4X-324058)
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