1-[2-(4-Methyl-1,3-thiazol-5-yl)ethyl]-1H-indole-2,3-dione CAS 681837-50-3
| CAS No. | 681837-50-3 |
| Molecular Formula | C14H12N2O2S |
| Molecular Weight | 272.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-[2-(4-Methyl-1,3-thiazol-5-yl)ethyl]-1H-indole-2,3-dione (CAS 681837-50-3), a certified reference material (molecular formula C14H12N2O2S, MW 272.32 g/mol) for analytical method development and quality control.
The molecular framework of 1-[2-(4-Methyl-1,3-thiazol-5-yl)ethyl]-1H-indole-2,3-dione (C14H12N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[2-(4-Methyl-1,3-thiazol-5-yl)ethyl]-1H-indole-2,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12N2O2S |
| Molecular Weight | 272.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 2-[2-(2-Methyl-1,3-thiazol-4-yl)ethyl]-2,3-dihydro-1H-isoindole-1,3-dione (CAS 524704-33-4)
- (3-(Thiazol-4-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225181-02-0)
- (3-(Thiazol-5-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225179-79-1)
- Thiazol-2-yl(4-(trifluoromethoxy)phenyl)methanone (CAS 1443340-39-3)
- Thiazol-2-yl(2-(trifluoromethoxy)phenyl)methanone (CAS 1443348-08-0)
- [2-(Thiazol-2-ylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester (CAS 1043390-61-9)
- 2-[2-(4-methyl-1,3-thiazol-5-yl)-1h-1,3-benzodiazol-1-yl]acetic acid (CAS 1094744-10-1)
- Thiazol-2-ylmethyl 2H-chromene-3-carboxylate (CAS 1252178-97-4)
Recommended Standards
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- Acetyl tetrapeptide-9(Dermican LS 9837) (CAS 928006-50-2)
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