(E)-3-(3-fluoro-2-hydroxyphenyl)acrylic acid CAS 682805-04-5
| CAS No. | 682805-04-5 |
| Molecular Formula | C9H7FO3 |
| Molecular Weight | 182.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-3-(3-fluoro-2-hydroxyphenyl)acrylic acid.
CATO supplies (E)-3-(3-fluoro-2-hydroxyphenyl)acrylic acid (CAS 682805-04-5), a certified reference material (molecular formula C9H7FO3, MW 182.15 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (E)-3-(3-fluoro-2-hydroxyphenyl)acrylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-3-(3-fluoro-2-hydroxyphenyl)acrylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7FO3 |
| Molecular Weight | 182.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related E Standards
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Recommended Standards
- (E)-3-(2-fluoro-4-hydroxyphenyl)acrylic acid (CAS 696589-23-8)
- (E)-3-(3-fluoro-4-hydroxyphenyl)acrylic acid (CAS 56926-74-0)
- (3S,4S,5S,6R)-3-fluoro-6-(hydroxymethyl)tetrahydro-2H-pyran-2,4,5-triol (CAS 31077-88-0)
- (E)-3-(5-fluoro-2-hydroxyphenyl)acrylic acid (CAS 75487-91-1)
- 3-Chloro-2,4,6-trimethylaniline (CAS 67396-82-1)
- 3-(Ethoxycarbonyl)-1-(2-ethylphenyl)-5-methyl-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264043-12-0)
- 4-ANDROSTEN-3β, 17β-DIOL-11-ONE (CAS 14485-67-7)
- 5-(4-Chlorophenyl)-3-(4-methoxyphenyl)isoxazole (CAS 24097-20-9)
- 2-(Carboxy(hydroxy)methyl)-7-methoxybenzo[d]oxazole (CAS 1806524-51-5)
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