Ethyl 7-chloro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate CAS 68301-92-8
| CAS No. | 68301-92-8 |
| Molecular Formula | C16H12ClNO4 |
| Molecular Weight | 317.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 7-chloro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ethyl 7-chloro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate (CAS 68301-92-8), a certified reference material (molecular formula C16H12ClNO4, MW 317.72 g/mol) for analytical method development and quality control.
Based on its molecular formula C16H12ClNO4, Ethyl 7-chloro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 317.72 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 7-chloro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12ClNO4 |
| Molecular Weight | 317.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Methyl 5-((6-chloro-4-oxoquinolin-1(4H)-yl)methyl)furan-2-carboxylate (CAS 1215388-37-6)
- 2-(3-Chloro-4-oxazol-2-yl-benzoyl)-3-hydroxy-cyclohex-2-enone (CAS 1231606-47-5)
- 2-(2-Chloro-4-oxazol-2-yl-benzoyl)-3-hydroxy-cyclohex-2-enone (CAS 1231655-65-4)
- (2-Chloro-5-nitrophenyl)methyl (2E)-3-phenylprop-2-enoate (CAS 328263-22-5)
- 1-(4-Chloro-2,5-difluorobenzoyl)piperidine-4-carbohydrazide (CAS 388094-06-2)
- 3-Chloro-2-[2-(prop-2-yn-1-ylsulfanyl)-1H-imidazol-1-yl]-5-(trifluoromethyl)pyridine (CAS 338956-46-0)
- 3-Chloro-2-methyl-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439120-56-6)
- 3-Chloro-2-methyl-7-(thiophen-2-yl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 866143-92-2)
Recommended Standards
- Carprofen EP Impurity A (CAS 252288-17-8)
- Methyl 7-chloro-2-ethyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate (CAS 338778-37-3)
- 5-((4-Chlorophenyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbonitrile (CAS 318239-38-2)
- n-(1,3-Dioxaindan-5-yl)-2-chloro-3-oxo-3-phenylpropanamide (CAS 848316-27-8)
- 3-((3-Hydroxyphenyl)amino)tetrahydrothiophene 1,1-dioxide hydrochloride (CAS 1059602-41-3)
- 1,3-Dimesityl-4,5-dihydro-1H-imidazol-3-ium tetrafluoroborate (CAS 245679-18-9)
- methyl 2-chloropyrrolo[2,1-f][1,2,4]triazine-7-carboxylate (CAS 2306269-11-2)
- N-(2-((4-chloro-3-nitrophenyl)amino)-2-oxoethyl)-N-cyclohexyl-3-nitrobenzamide (CAS 332156-19-1)
- 2-Bromo-5-nitrocinnamic acid (CAS 1262013-78-4)
- 4-(tert-Butyl)phenethyl acetate (CAS 66619-08-7)
- 1-(5-Bromonaphthalen-1-yl)cyclopropan-1-amine (CAS 1781089-64-2)
- 5-(2,2-Dimethoxyethyl)-4-(3-(trifluoromethyl)phenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 477850-72-9)
- 4-(chloromethyl)-1-(2-methanesulfonylethyl)-3,5-dimethyl-1H-pyrazole hydrochloride (CAS 1803583-05-2)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com