2-(4-Bromo-2-fluorobenzyl)malonic acid CAS 683216-89-9
| CAS No. | 683216-89-9 |
| Molecular Formula | C10H8BrFO4 |
| Molecular Weight | 291.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 291.07 g/mol gives 2-(4-Bromo-2-fluorobenzyl)malonic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(4-Bromo-2-fluorobenzyl)malonic acid (CAS 683216-89-9), a certified reference material (molecular formula C10H8BrFO4, MW 291.07 g/mol) for analytical method development and quality control.
2-(4-Bromo-2-fluorobenzyl)malonic acid (C10H8BrFO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(4-Bromo-2-fluorobenzyl)malonic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8BrFO4 |
| Molecular Weight | 291.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 3-Bromo-7-(trifluoromethyl)quinolin-4-amine (CAS 1065088-43-8)
- 3-Bromo-8-(trifluoromethyl)quinolin-4-amine (CAS 1065088-48-3)
- 4-Bromo-5-phenyl-3-(trifluoromethyl)-1H-pyrazole (CAS 1119391-55-7)
- 4-Bromo-1-(4-(trifluoromethyl)phenyl)-1H-pyrazole (CAS 1203556-18-6)
- 4-Bromo-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole (CAS 1353855-69-2)
- 4-Bromo-1-(4-(trifluoromethyl)phenyl)-1H-imidazole (CAS 1353856-15-1)
- 4-Bromo-1-(3-(trifluoromethyl)phenyl)-1H-imidazole (CAS 1353856-19-5)
- 2-Bromo-5-fluoro-3,6-dimethylterephthalic acid (CAS 1555757-16-8)
Recommended Standards
- 1-(2-Bromophenyl)-5-(trifluoromethyl)-1H-pyrazole (CAS 497833-00-8)
- 3-(4-Bromophenyl)-5-(trifluoromethyl)-1H-pyrazole (CAS 219986-65-9)
- (2-Methylindolizine-3-carbonyl)phosphoramidic dichloride (CAS 885457-12-5)
- 4-bromo-1-phenyl-5-(trifluoromethyl)-1H-pyrazole (CAS 497833-01-9)
- Hexylhydrazine hydrochloride (CAS 79201-41-5)
- 4-Hydroxy-1-benzofuran-5-carboxylic acid (CAS 487-56-9)
- 4-(Thiophen-2-yl)benzaldehyde (CAS 107834-03-7)
- N-(3-Amino-4-chlorophenyl)-2-(2-chlorophenoxy)-propanamide (CAS 1020055-01-9)
- 5-Iodo-1H-1,2,4-triazole-3-carboxylic acid (CAS 36033-56-4)
- 2-Ethyl-2-propyl-1-hexanol (CAS 54461-00-6)
- Methyl 2-amino-3-bromo-5-fluorobenzoate (CAS 864293-46-9)
- 4-Nitro-1,2-bis(trifluoromethyl)benzene (CAS 1978-20-7)
- 2-[(Cyclopropylcarbonyl)amino]benzoic Acid (CAS 40057-21-4)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
Why CATO?
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