5-Bromo-1,6-naphthyridine CAS 68336-81-2
| CAS No. | 68336-81-2 |
| Molecular Formula | C8H5BrN2 |
| Molecular Weight | 209.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-1,6-naphthyridine.
5-Bromo-1,6-naphthyridine (CAS 68336-81-2), molecular formula C8H5BrN2 and molecular weight 209.04 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution, 5-Bromo-1,6-naphthyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 209.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Bromo-1,6-naphthyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5BrN2 |
| Molecular Weight | 209.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- Methyl 4-Bromo-3-oxopentanoate (CAS 105983-77-5)
- methyl 5-bromo-1H-imidazole-4-carboxylate (CAS 1093261-46-1)
- 5-bromo-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 1222174-93-7)
- Methyl 3-bromo-2-oxopentanoate (CAS 137267-36-8)
- methyl 4-bromo-1H-imidazole-2-carboxylate (CAS 1622843-37-1)
- 3-bromo-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 173841-05-9)
- 4-Bromo-2,6-naphthyridine (CAS 1782910-98-8)
- 3-Bromo-1,6-naphthyridine (CAS 17965-73-0)
Recommended Standards
- 4-Bromoquinazoline (CAS 354574-59-7)
- 5-Bromo-1H-inden-1-one (CAS 338989-48-3)
- 4-Bromo-2,7-naphthyridine (CAS 28002-16-6)
- 5-Bromo-4-fluorothiophene-2-carbaldehyde (CAS 2089378-00-5)
- (S)-3-(Boc-amino)-4-(3-indolyl)butanoic Acid (CAS 229639-48-9)
- 5-Cyclopropoxy-2-isopropyl-4-methylpyridine (CAS 1243442-97-8)
- 5-(Difluoromethoxy)benzo[d]oxazol-2-amine (CAS 1806532-29-5)
- 3-(2,5-Dioxopyrrolidin-1-yl)-N-(3,5,7-trimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide (CAS 868369-91-9)
- 2-Methyl-1H-indole-5-sulfonic acid (CAS 67786-12-3)
- tert-Butyldimethyl(thiophen-2-yl)silane (CAS 163079-25-2)
- N-hydroxy-2-((3-(trifluoromethyl)pyridin-2-yl)thio)acetimidamide (CAS 263762-04-5)
- 1H-indole-5-ethanol (CAS 281232-81-3)
- cis-3-Hexenyl lactate (CAS 61931-81-5)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
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