2-Methyl-3(or 5)-(methylthio)pyrazine CAS 68378-12-1

Description

Compared with other compounds in its class, the molecular weight of 140.21 g/mol gives 2-Methyl-3(or 5)-(methylthio)pyrazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Methyl-3(or 5)-(methylthio)pyrazine (CAS 68378-12-1), molecular formula C6H8N2S and molecular weight 140.21 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Methyl-3(or 5)-(methylthio)pyrazine (C6H8N2S) is characterized by a nitrile group, sulfur-containing functionality, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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