2,4-Difluoro-6-((trimethylsilyl)ethynyl)aniline CAS 684250-21-3
| CAS No. | 684250-21-3 |
| Molecular Formula | C11H13F2NSi |
| Molecular Weight | 225.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,4-Difluoro-6-((trimethylsilyl)ethynyl)aniline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,4-Difluoro-6-((trimethylsilyl)ethynyl)aniline (CAS 684250-21-3) is a high-purity analytical reference standard with the molecular formula C11H13F2NSi and a molecular weight of 225.31 g/mol.
The molecular framework of 2,4-Difluoro-6-((trimethylsilyl)ethynyl)aniline (C11H13F2NSi) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H13F2NSi |
| Molecular Weight | 225.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2,3-Difluoro-4-((trimethylsilyl)ethynyl)aniline (CAS 2149597-51-1)
- 3,4-Difluoro-N-(thiophen-2-ylmethyl)aniline (CAS 1019494-57-5)
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- Diacerein-d6 (CAS CATO-C4X-108119)
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- 4-(2,4-Dimethoxyphenyl)-2,2-dimethyl-4-oxobutyric acid (CAS 951885-24-8)
- 2-(Dimethylamino)-6-methylpyrimidin-4(3H)-one (CAS 19810-73-2)
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- 2-(1,3-Dioxo-2,3-dihydro-1h-isoindol-2-yl)ethanimidamide hydrochloride (CAS 1920-12-3)
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