1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium acetate 2-amino-2-(hydroxymethyl)propane-1,3-diol acetate 6850-28-8 CHEBI:66869 TRIS acetate salt [2-hydroxy-1,1-bis(hydroxymethyl)ethyl]ammonium acetate tris acetate tris(hydroxymethyl)aminomethane acetate tris(hydroxymethyl)aminomethane acetate salt trizma acetate CAS 6850-28-8

Purity 97%+In StockPharmaceutical Standards
CAS No.6850-28-8
Molecular FormulaC4H11NO3
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium acetate 2-amino-2-(hydroxymethyl)propane-1,3-diol acetate 6850-28-8 CHEBI:66869 TRIS acetate salt [2-hydroxy-1,1-bis(hydroxymethyl)ethyl]ammonium acetate tris acetate tris(hydroxymethyl)aminomethane acetate tris(hydroxymethyl)aminomethane acetate salt trizma acetate CAS 6850-28-8 chemical structure

Description

As a certified reference material (CRM), 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium acetate 2-amino-2-(hydroxymethyl)propane-1,3-diol acetate 6850-28-8 CHEBI:66869 TRIS acetate salt [2-hydroxy-1,1-bis(hydroxymethyl)ethyl]ammonium acetate tris acetate tris(hydroxymethyl)aminomethane acetate tris(hydroxymethyl)aminomethane acetate salt trizma acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium acetate 2-amino-2-(hydroxymethyl)propane-1,3-diol acetate 6850-28-8 CHEBI:66869 TRIS acetate salt [2-hydroxy-1,1-bis(hydroxymethyl)ethyl]ammonium acetate tris acetate tris(hydroxymethyl)aminomethane acetate tris(hydroxymethyl)aminomethane acetate salt trizma acetate (CAS 6850-28-8) is a high-purity analytical reference standard with the molecular formula C4H11NO3C2H4O2 and a molecular weight of 181.19 g/mol.

The molecular framework of 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium acetate 2-amino-2-(hydroxymethyl)propane-1,3-diol acetate 6850-28-8 CHEBI:66869 TRIS acetate salt [2-hydroxy-1,1-bis(hydroxymethyl)ethyl]ammonium acetate tris acetate tris(hydroxymethyl)aminomethane acetate tris(hydroxymethyl)aminomethane acetate salt trizma acetate (C4H11NO3C2H4O2) is characterized by a carbohydrate-derived structure, an amide group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

Physical & Chemical Properties

Molecular FormulaC4H11NO3 C2H4O2
Molecular Weight181.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)1958
Nitrogen Atoms1

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