2-Chloro-1-(4-hydroxy-3-methoxyphenyl)propan-1-one CAS 68505-86-2
| CAS No. | 68505-86-2 |
| Molecular Formula | C10H11ClO3 |
| Molecular Weight | 214.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-1-(4-hydroxy-3-methoxyphenyl)propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloro-1-(4-hydroxy-3-methoxyphenyl)propan-1-one (CAS 68505-86-2), molecular formula C10H11ClO3 and molecular weight 214.65 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-1-(4-hydroxy-3-methoxyphenyl)propan-1-one (C10H11ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO3 |
| Molecular Weight | 214.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 4-Chloro-1-cyclopentyl-1H-pyrazole-3-carboxylic acid (CAS 1006451-33-7)
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- 4-Chloro-1-cyclopentyl-1h-pyrazole-5-carboxylic acid (CAS 1006493-95-3)
- 6-Chloro-N-(2-methoxyethyl)pyridine-3-carboxamide (CAS 1016741-22-2)
- 2-Chloro-5-phenylnicotinonitrile (CAS 10177-10-3)
- Ethyl 2-chloro-3-(methylamino)isonicotinate (CAS 1034132-15-4)
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Recommended Standards
- 2-Chloro-1-(3,5-dimethoxyphenyl)ethan-1-one (CAS 72612-04-5)
- 2-Chloro-1,10-phenanthroline (CAS 7089-68-1)
- 2-Chloro-1-(3,4-dimethoxyphenyl)ethanone (CAS 20601-92-7)
- 2-Chloro-4-ethoxy-5-methoxybenzaldehyde (CAS 443125-57-3)
- 2-((6-(Benzo[d][1,3]dioxol-5-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-N-(2-chloropyridin-3-yl)acetamide (CAS 625378-09-8)
- N-(3-Chlorophenyl)-3-nitrobenzamide (CAS 2585-22-0)
- 5-Bromo-2-fluorophenylacetic Acid (CAS 883514-21-4)
- 3-Methyl-4-(1h-1,2,3,4-tetrazol-1-yl)benzene-1-sulfonyl chloride (CAS 1099632-63-9)
- 5-Chloro-2-isobutylpyridine (CAS 2197051-12-8)
- n-Carbamoyl-2-((2-chloro-4-methylphenyl)amino)acetamide (CAS 1040311-83-8)
- 6-Fluoro-2,2,4-trimethyl-1,2-dihydroquinoline (CAS 50772-15-1)
- 2-Hydroxy-4-(tetrahydropyran-2-yloxy)acetophenone (CAS 111841-07-7)
- Methyl 4-chloro-4-oxobut-2-enoate (CAS 78140-66-6)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
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