N-[3-(1,3-Benzoxazol-2-yl)-4-fluorophenyl]-4-methylbenzamide CAS 685108-48-9
| CAS No. | 685108-48-9 |
| Molecular Formula | C21H15FN2O2 |
| Molecular Weight | 346.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-[3-(1,3-Benzoxazol-2-yl)-4-fluorophenyl]-4-methylbenzamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N-[3-(1,3-Benzoxazol-2-yl)-4-fluorophenyl]-4-methylbenzamide (CAS 685108-48-9), a certified reference material (molecular formula C21H15FN2O2, MW 346.35 g/mol) for analytical method development and quality control.
N-[3-(1,3-Benzoxazol-2-yl)-4-fluorophenyl]-4-methylbenzamide (C21H15FN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-[3-(1,3-Benzoxazol-2-yl)-4-fluorophenyl]-4-methylbenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H15FN2O2 |
| Molecular Weight | 346.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 2-(1,3-Benzoxazol-2-ylsulfanyl)-N-(3,4-dichlorophenyl)acetamide (CAS 297150-39-1)
- 1-[4-(1,3-Benzoxazol-2-yl)phenyl]-4,4-dimethyl-1,4-dihydropyrimidine-2-thiol (CAS 1142213-27-1)
- 2-(1,3-Benzoxazol-2-yl)-4-(5-fluoro-1h-indol-3-yl)-3-oxobutanenitrile (CAS 1384603-79-5)
- N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2,3-dichlorobenzamide (CAS 328251-61-2)
- N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2,4-dichlorobenzamide (CAS 313549-24-5)
- 1142207-17-7 n-[4-(1,3-benzoxazol-2-yl)phenyl]-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142207-17-7)
- 5-[(1,2-Benzoxazol-3-yl)methyl]-4-phenyl-4H-1,2,4-triazole-3-thiol (CAS 860785-59-7)
- 1365963-80-9 N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-chloropropanamide MFCD22056589 (CAS 1365963-80-9)
Recommended Standards
- N-(2-(1-Methyl-1H-indol-3-yl)ethyl)-2-(trifluoromethyl)benzamide (CAS 920537-42-4)
- Flurbiprofen Impurity 14 (CAS CATO-C4X-144414)
- 4-Methyl-5-(2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazol-4-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 955962-78-4)
- Pazufloxacin Impurity 4 (CAS CATO-C4X-23324)
- 3-Isopropyl-5-methoxy-1H-indazole (CAS 1415740-54-3)
- 3’-(Trifluoromethyl)biphenyl-3-amine Hydrochloride (CAS 811842-42-9)
- (4-(2-(Methylthio)ethyl)phenyl)methanamine (CAS 1894762-79-8)
- 915922-96-2 4-Chloro-5,6-dimethyl-2-(pyrrolidin-1-yl)pyrimidine DTXSID40650902 (CAS 915922-96-2)
- Benzyl 2-(4-fluoro-2-methylphenyl)-4-oxo-3,4-dihydropyridine-1(2H)-carboxylate (CAS 414909-98-1)
- 3-Oxo-3-(3,4,5-trimethyl-1H-pyrazol-1-yl)propanenitrile (CAS 477710-14-8)
- 3,5,5-Trimethylcyclohexane-1,2-dione (CAS 57696-89-6)
- 2-(2-Amino-4-methylphenyl)acetonitrile (CAS 861068-42-0)
- 2-Ethyl-4-hydroxy-5-methylfuran-3(2H)-one (CAS 27538-10-9)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
Why CATO?
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