6-Hydroxyindolin-2-one CAS 6855-48-7
| CAS No. | 6855-48-7 |
| Molecular Formula | C8H7NO2 |
| Molecular Weight | 149.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 6-Hydroxyindolin-2-one (CAS 6855-48-7), a certified reference material (molecular formula C8H7NO2, MW 149.15 g/mol) for analytical method development and quality control.
The molecular framework of 6-Hydroxyindolin-2-one (C8H7NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 6-Hydroxyindolin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7NO2 |
| Molecular Weight | 149.15 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Hydroxyindolin Standards
- 7-Hydroxyindolin-2-one (CAS 10238-74-1)
- 1-Hydroxyindolin-2-one (CAS 18108-55-9)
- 1-Hydroxyindolin-3-one (CAS 424837-29-6)
- 7-Hydroxyindolin-2-one (CAS 3416-18-2)
- 5-Ethyl-3-hydroxyindolin-2-one (CAS 1249072-63-6)
- 3-Ethyl-5-hydroxyindolin-2-one (CAS 1707394-15-7)
- 3-Ethyl-6-hydroxyindolin-2-one (CAS 1707563-45-8)
- 1-Ethyl-4-hydroxyindolin-2-one (CAS 173541-15-6)
Recommended Standards
- N-Methyl-7H-Purin-6-Amine (CAS 443-72-1)
- 5-Fluoro-6-methyl-1H-indole (CAS 1000343-16-7)
- rac 2-Aminothiazoline-4-carboxylic Acid-13C,15N2 (CAS 1346599-59-4)
- 2-(4-Fluoro-3-methylphenyl)acetonitrile (CAS 1000548-41-3)
- 4-(Pyridin-3-yl)cyclohexanone (CAS 103319-09-1)
- 3-(Thiophen-2-yl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazole-1-carboxamide (CAS 885269-92-1)
- 1,2-Difluoro-4-isocyanato-5-nitrobenzene (CAS 1249838-16-1)
- 1H-Pyrazolo[3,4-b]pyridine-3-carboxylic acid (CAS 116855-08-4)
- β,γ-Methyleneguanosine 5′-triphosphate sodium salt (CAS 10470-57-2)
- Chlorotripyrrolidinylphosphonium hexafluorophosphate (CAS 133894-48-1)
- 4-(5-Chlorothiazolo[5,4-d]pyrimidin-7-yl)morpholine (CAS 41975-14-8)
- 2λ⁶-thia-7-azaspiro[4.5]decane-2,2-dione hydrochloride (CAS 1909306-48-4)
- 2-Methyl-4-(pyrrolidin-1-yl)-1H-imidazole (CAS 799813-85-7)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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