3-(3-(2-Fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoic acid CAS 685525-40-0
| CAS No. | 685525-40-0 |
| Molecular Formula | C11H9FN2O3 |
| Molecular Weight | 236.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(3-(2-Fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-(3-(2-Fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 685525-40-0) is a high-purity analytical reference standard with the molecular formula C11H9FN2O3 and a molecular weight of 236.20 g/mol.
The molecular framework of 3-(3-(2-Fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoic acid (C11H9FN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H9FN2O3 |
| Molecular Weight | 236.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- Methyl 1-(4-fluorophenyl)-5-hydroxy-1H-pyrazole-3-carboxylate (CAS 1007073-76-8)
- Ethyl 3-(2-fluorophenyl)-1,2,4-oxadiazole-5-carboxylate (CAS 1018125-37-5)
- 3-(5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl)propanoic acid (CAS 1082828-46-3)
- 1-(4-Fluorophenyl)-4-methoxy-1h-pyrazole-3-carboxylic acid (CAS 1169973-47-0)
- 1-(2-Fluorophenyl)-5-methoxy-1H-pyrazole-3-carboxylic acid (CAS 1239726-11-4)
- Ethyl 3-(3-fluorophenyl)-1,2,4-oxadiazole-5-carboxylate (CAS 1239736-58-3)
- 1-(3-Fluorophenyl)-6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid (CAS 1273860-31-3)
- Ethyl 5-(3-fluorophenyl)-1,2,4-oxadiazole-3-carboxylate (CAS 1274477-51-8)
Recommended Standards
- 2-[1-(4-fluorophenyl)-5-oxo-2,5-dihydro-1h-pyrazol-3-yl]acetic acid (CAS 852851-74-2)
- 3-(6-Fluoro-4-oxo-4H-chromen-3-yl)propanoic acid (CAS 870704-01-1)
- 1-(4-Fluorophenyl)-N-methyl-4-nitro-1H-pyrazol-5-amine (CAS 318238-08-3)
- 3-[3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl]-propanoic acid (CAS 500025-07-0)
- N-(4-Cyclopropoxy-6-formylpyridin-3-yl)methanesulfonamide (CAS 1243389-15-2)
- 2-(6-Chloro-3-nitropyridin-2-yl)acetic acid (CAS 1807140-99-3)
- ((2R,3S,4R,5R)-5-(5-Amino-1H-imidazol-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 25635-88-5)
- Ethyl 6-oxospiro[2.5]octane-1-carboxylate (CAS 1447942-87-1)
- (4E)-3-(Chloromethyl)-4-(2,6-dichlorobenzylidene)-isoxazol-5(4H)-one 1142199-01-6 (CAS 1142199-01-6)
- 5-{[1,1'-Biphenyl]-4-yl}-3,4-dihydro-2h-pyrrole (CAS 102705-35-1)
- 3-Methoxy-4-((5-methylisoxazol-3-yl)methoxy)benzonitrile (CAS 876388-15-7)
- Arnicolide D (CAS 34532-68-8)
- 6-Bromo-3-cyano-2-(difluoromethyl)benzoic acid (CAS 1805581-20-7)
- Tirzepatide Impurity 59 (CAS CATO-C4X-324059)
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