4-chloro-1,6-naphthyridine CAS 6861-84-3
| CAS No. | 6861-84-3 |
| Molecular Formula | C8H15ClN2 |
| Molecular Weight | 174.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-chloro-1,6-naphthyridine is closely related to a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-chloro-1,6-naphthyridine (CAS 6861-84-3), molecular formula C8H15ClN2 and molecular weight 174.67 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, chlorine substitution, 4-chloro-1,6-naphthyridine is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 174.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-chloro-1,6-naphthyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H15ClN2 |
| Molecular Weight | 174.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
- 4-Chloro-5-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1020056-56-7)
- 6-chloro-1H-indol-5-amine (CAS 1049022-23-2)
- 6-chloro-3-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1211531-25-7)
- 7-chloro-1,2,3,4-tetrahydro-1,8-naphthyridine (CAS 1303588-27-3)
- 8-chloro-1,7-naphthyridine (CAS 13058-77-0)
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- 6-chloro-1,7-naphthyridine (CAS 1309379-17-6)
- 3-chloro-2,7-naphthyridine (CAS 1309379-18-7)
Recommended Standards
- 4-(chloromethyl)-1H-indazole (CAS 944898-78-6)
- 4-chloro-1-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 74420-05-6)
- 3-cyclohexylpropanoyl chloride (CAS 39098-75-4)
- 4-chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 307951-53-7)
- (S)-5,7-dihydroxy-6,8-bis(2-hydroxybenzyl)-2-phenylchroman-4-one (CAS 58779-09-2)
- 5-(Difluoromethoxy)-2-fluoropyridine (CAS 130318-80-8)
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- 3-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-thioxothiazolidin-4-one (CAS 62329-47-9)
- Methyl 6-O-Trityl-α-D-galactopyranoside (CAS 35920-83-3)
- 2-(Methylsulfanyl)-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbaldehyde (CAS 1148027-11-5)
- CAS 32479-94-0 (CAS 32479-94-0)
- 1-(3-(Azetidin-1-ylmethyl)phenyl)undecane-1,8-dione (CAS 898761-20-1)
- (Met(O)2?)-Glucagon (1-29) (human, rat, porcine) (CAS 75217-63-9)
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