4,4-Difluoro-1,4'-bipiperidine CAS 686298-08-8
| CAS No. | 686298-08-8 |
| Molecular Formula | C10H18F2N2 |
| Molecular Weight | 204.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,4-Difluoro-1,4'-bipiperidine.
CATO supplies 4,4-Difluoro-1,4'-bipiperidine (CAS 686298-08-8), a certified reference material (molecular formula C10H18F2N2, MW 204.26 g/mol) for analytical method development and quality control.
The molecular framework of 4,4-Difluoro-1,4'-bipiperidine (C10H18F2N2) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,4-Difluoro-1,4'-bipiperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H18F2N2 |
| Molecular Weight | 204.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoro Standards
- 7,7-Difluoro-9-methyl-2,9-diazaspiro[5.5]Undecane (CAS 1509285-21-5)
- 7,7-Difluoro-2-methyl-2,9-diazaspiro[5.5]Undecane (CAS 1521588-97-5)
- 1,1-Difluoro-3-methyl-3,9-diazaspiro[5.5]Undecane (CAS 1780749-59-8)
- 1,1-Difluoro-9-methyl-3,9-diazaspiro[5.5]Undecane (CAS 1785502-42-2)
- 3',3'-Difluoro-1,4'-bipiperidine (CAS 1934439-49-2)
- 3,3-Difluoro-1,4'-bipiperidine (CAS 864356-23-0)
- 3,5-Difluoro-2-propoxybenzenethiol (CAS 1379317-09-5)
- (3,4-Difluoro-5-methoxyphenyl)(ethyl)sulfane (CAS 1379324-74-9)
Recommended Standards
- 4,4,5,7-Tetramethylchroman-2-one (CAS 40662-14-4)
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- 4-(O-tolyl)tetrahydro-2H-pyran-4-carbaldehyde (CAS 902836-58-2)
- 4,4-Dimethyl-2-phenylpent-2-enoic acid (CAS 2102729-59-7)
- 1-(3,4-Dimethoxyphenyl)ethanol (CAS 5653-65-6)
- [Met5,Arg6,Gly7,Leu8] Enkephalin (CAS 80501-44-6)
- ethyl 5-(4-fluorophenyl)-1,3-oxazole-4-carboxylate (CAS 127919-31-7)
- Papaverine-d3 Hydrochloride (CAS 113718-66-4)
- Hexahydropentalen-3a(1H)-amine hydrochloride (CAS 2402829-41-6)
- 2-(6-Bromo-1H-indol-3-yl)acetonitrile (CAS 152213-61-1)
- 4-(1-Ethyl-1H-benzo[d]imidazol-2-yl)butanoic acid (CAS 878436-85-2)
- 2,5-Bis(5-bromothiophen-2-yl)thiazolo[5,4-d]thiazole (CAS 1227366-41-7)
- N-(2-Methoxyethyl)-4-nitro-2-(trifluoromethyl)aniline (CAS 1183236-47-6)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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