3-(4-Ethoxyphenyl)-2-(ethylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one CAS 686772-58-7
| CAS No. | 686772-58-7 |
| Molecular Formula | C16H18N2O2S2 |
| Molecular Weight | 334.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(4-Ethoxyphenyl)-2-(ethylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one (CAS 686772-58-7), molecular formula C16H18N2O2S2 and molecular weight 334.46 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(4-Ethoxyphenyl)-2-(ethylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one (C16H18N2O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(4-Ethoxyphenyl)-2-(ethylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H18N2O2S2 |
| Molecular Weight | 334.46 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
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Recommended Standards
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- 4-Methyl-2-phenyl-5-(2-phenyl-1,3-thiazol-4-yl)-1,3-thiazole (CAS 7520-97-0)
- N,N-Dimethyl-N′-2-thiazolylsulfamide (CAS 349419-27-8)
- Fmoc-N-Me-Met-OH (CAS 84000-12-4)
- 3-(trifluoromethyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid (CAS 1797367-92-0)
- n-(2-Iodophenyl)methanesulfonamide (CAS 116547-92-3)
- N-(3-chloro-2,6-dimethoxybenzoyl)-N'-(2,3,4,5,6-pentafluorophenyl)urea (CAS 222540-41-2)
- tert-Butyl (2-amino-4-(tert-butyl)phenyl)carbamate (CAS 335013-37-1)
- (4E)-4-[1-(Dimethylamino)-2-(1H-1,2,4-triazol-1-yl)ethylidene]-2-phenyl-4,5-dihydro-1,3-oxazol-5-one (CAS 866010-29-9)
- 3-(2-Cyanophenyl)-5-fluorobenzoic acid (CAS 1352317-82-8)
- 3-(Benzylamino-methyl)-6,8-dimethyl-1H-quinolin-2-one (CAS 436087-64-8)
- D-[γ-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226254)
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