3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-amine CAS 68774-80-1

Purity 97%+In StockPharmaceutical Standards
CAS No.68774-80-1
Molecular FormulaC6H7N5
Molecular Weight149.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-amine CAS 68774-80-1 chemical structure

Description

3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-amine (CAS 68774-80-1), molecular formula C6H7N5 and molecular weight 149.15 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-amine (C6H7N5) is characterized by a nitrile group, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H7N5
Molecular Weight149.15 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1976
Nitrogen Atoms5

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