Bromocriptine Impurity 15 CAS 68944-89-8
| CAS No. | 68944-89-8 |
| Molecular Formula | C32H40BrN5O5 |
| Molecular Weight | 654.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Bromocriptine Impurity 15 (CAS 68944-89-8, C32H40BrN5O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Bromocriptine Impurity 15 (C32H40BrN5O5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C32H40BrN5O5 |
| Molecular Weight | 654.59 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
Related Bromocriptine Standards
- Bromocriptine EP Impurity C (CAS 65700-36-9)
- Bromocriptine EP Impurity F (CAS 82773-21-5)
- Bromocriptine (CAS 25614-03-3)
- Bromocriptine-13C-d3 (CAS CATO-C4X-13612)
- Bromocriptine Methyl EtherDiscontinued (CAS 1349233-25-5)
- Bromocriptine 2-Methylbutyl Analogue (CAS 157135-98-3)
- Bromocriptine Impurity 13 (CAS 157135-99-4)
- Bromocriptine Mesilate EP Impurity G (CAS CATO-C4X-13618)
Recommended Standards
- Troxerutin Impurity 5 (CAS 125092-04-8)
- Troxerutin Impurity 4 (CAS 23869-24-1)
- Troxerutin Impurity 3 (CAS 13190-92-6)
- N-[3,5-Bis(pyridin-2-yl)-4H-1,2,4-triazol-4-yl]-3-(trifluoromethyl)-N-[3-(trifluoromethyl)benzenesulfonyl]benzene-1-sulfonamide (CAS 320418-52-8)
- Bupivacaine EP Impurity C (CAS 1797894-80-4)
- Trelagliptin Impurity 62 (CAS CATO-C4X-104662)
- Phenylephrine Impurity 62(Phenylephrine Isoquinolinone Analog) (CAS CATO-C4X-146762)
- Methyl 5-(hydroxymethyl)-2-methylfuran-3-carboxylate (CAS 15341-69-2)
- 2,4,7-Trichloro-1,3-benzothiazole (CAS 898747-91-6)
- 2-Amino-3-(2-fluoro-4-methoxyphenyl)propanoic acid (CAS 54788-29-3)
- 6-Bromo-3-iodo-1-methyl-1H-indazole (CAS 1260741-78-3)
- (2E)-N-Methyl-3-(2-nitrophenyl)acrylamide (CAS 600122-64-3)
- 2-(Azepan-2-yl)-1-(thiophen-3-yl)ethan-1-one (CAS 1520322-31-9)
- Semaglutide impurity 47 (CAS CATO-C4X-222647)
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