Prilocaine Impurity 21 CAS 69003-28-7
| CAS No. | 69003-28-7 |
| Molecular Formula | C10H11Cl2NO |
| Molecular Weight | 232.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 232.11 g/mol gives Prilocaine Impurity 21 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Prilocaine Impurity 21 (CAS 69003-28-7, C10H11Cl2NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H11Cl2NO, Prilocaine Impurity 21 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 232.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Prilocaine Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11Cl2NO |
| Molecular Weight | 232.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Prilocaine Standards
- Prilocaine Impurity 20 (CAS 1072844-57-5)
- Prilocaine Impurity 6 (Lidocaine Impurity 16) (CAS 39084-88-3)
- Prilocaine impurity 54 (CAS CATO-C4X-193454)
- Prilocaine impurity 46 (CAS CATO-C4X-193446)
- Prilocaine impurity 47 (CAS CATO-C4X-193447)
- Prilocaine impurity 51 (CAS CATO-C4X-193451)
- Prilocaine impurity 52 (CAS CATO-C4X-193452)
- Prilocaine Impurity 56 (CAS CATO-C4X-193456)
Recommended Standards
- Etomidate Impurity 76 (CAS CATO-C4X-188476)
- 3-(4-Bromo-3,5-dimethyl-1h-pyrazol-1-yl)propan-1-amine (CAS 1000802-72-1)
- Etomidate Impurity 44 (CAS 39096-80-5)
- 2-Nitro-5-(trifluoromethoxy)benzonitrile (CAS 1003708-58-4)
- Salbutamol Impurity 176 (CAS CATO-C4X-1176176)
- Cyclophosphamide impurity 41 (CAS CATO-C4X-230641)
- Bedaquiline Impurity 9 (CAS 22422-69-1)
- 2-Amino-3-(4-bromo-1H-pyrazol-1-yl)propanenitrile (CAS 1249444-29-8)
- Methyl 1-Benzyl-2,5-dihydropyrrole-3-carboxylate (CAS 101046-34-8)
- 1-(2-amino-4-nitrophenyl)ethan-1-one (CAS 56515-58-3)
- 5-Chloro-4-methylthiophene-2-carbaldehyde (CAS 65782-04-9)
- 2,2,8,8-Tetramethyl-3,5,7-nonanetrione (CAS 104779-75-1)
- 2-(1H-Pyrrolo[2,3-b]pyridin-5-yl)isoindoline-1,3-dione (CAS 923583-83-9)
- Allo-D-Ile12-Tirzepatide (CAS CATO-CPTD788963)
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