4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenol CAS 69045-85-8
| CAS No. | 69045-85-8 |
| Molecular Formula | C12H8F3NO2 |
| Molecular Weight | 255.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 255.19 g/mol gives 4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenol (CAS 69045-85-8), molecular formula C12H8F3NO2 and molecular weight 255.19 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenol (C12H8F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 255.19 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8F3NO2 |
| Molecular Weight | 255.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related trifluoromethyl Standards
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- Methyl 2-(trifluoromethyl)quinoline-6-carboxylate (CAS 1154743-11-9)
- 3-Methyl-5-(4-(trifluoromethyl)phenyl)isoxazole-4-carbaldehyde (CAS 1208081-38-2)
- 1-(2-(Trifluoromethyl)benzyl)-1H-pyrrole-2,5-dione (CAS 140481-00-1)
- 6-Methyl-2-(trifluoromethyl)quinoline-4-carboxylic acid (CAS 18706-40-6)
- 1-(3-(3-(Trifluoromethyl)phenyl)isoxazol-5-yl)ethan-1-one (CAS 264616-44-6)
- 1-(3-(Trifluoromethyl)phenyl)-1H-pyrrole-2-carboxylic acid (CAS 233692-71-2)
- 1-Methyl-3-(3-(trifluoromethyl)phenyl)-1H-pyrrole-2,5-dione (CAS 89931-82-8)
Recommended Standards
- 3-(1H-Pyrrol-1-yl)-5-(trifluoromethyl)benzoic acid (CAS 276861-97-3)
- 4-Hexylbenzyl Bromide (CAS 60982-72-1)
- 2,3-Dicyano-1,4-dihydroxy-5-nitronaphthalene (CAS 4655-62-3)
- 4-Methyl-3-(2,2,2-trifluoroacetyl)quinolin-2(1H)-one (CAS 727-58-2)
- 1-(3-Fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-carbothioamide (CAS 1019187-19-9)
- 4,4'-Azanediyldibenzonitrile (CAS 36602-05-8)
- 1-(1-(2,5-Dimethoxyphenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrol-3-yl)-N-(4-methoxyphenyl)methanimine (CAS 478032-28-9)
- 2-(4-Chlorophenyl)-5-(2-{[(4-chlorophenyl)methyl]sulfanyl}phenyl)-1,3,4-oxadiazole (CAS 339104-03-9)
- 3-Amino-N-(thiazol-2-yl)propanamide hydrochloride (CAS 1046757-40-7)
- 1-(2-methylpropyl)-5-(trifluoromethyl)-1H-imidazol-2-amine (CAS 1803584-90-8)
- 4-(3-Chloro-2-fluorophenyl)pyrimidin-2-amine (CAS 671754-13-5)
- Benzyl-PEG6-amine (CAS 86770-78-7)
- 3-(Azetidin-3-yloxy)pyridine (CAS 224818-30-8)
- Peptide WE-14 (CAS 115136-18-0)
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