4-(4-Benzylpiperazin-1-yl)-1H-indole dihydrochloride hydrate CAS 690632-86-1
| CAS No. | 690632-86-1 |
| Molecular Formula | C19H21N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(4-Benzylpiperazin-1-yl)-1H-indole dihydrochloride hydrate (CAS 690632-86-1) is a high-purity analytical reference standard with the molecular formula C19H21N3HClH2O and a molecular weight of 345.87 g/mol.
The molecular framework of 4-(4-Benzylpiperazin-1-yl)-1H-indole dihydrochloride hydrate (C19H21N3HClH2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 4-(4-Benzylpiperazin-1-yl)-1H-indole dihydrochloride hydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H21N3 2*HCl H2O |
| Molecular Weight | 345.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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- 2-(4-Benzylpiperazin-1-yl)isonicotinonitrile (CAS 1016862-98-8)
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- (2Z)-2-[(4-Benzylpiperazin-1-yl)methylidene]-4,4-dimethyl-3-oxopentanenitrile (CAS 1024869-99-5)
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Recommended Standards
- 3-(Tert-butoxycarbonyl)-3-azabicyclo[3.2.1]Octane-1-carboxylic acid (CAS 1781098-86-9)
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- 8A-(4-Methoxyphenyl)-octahydropyrrolo[1,2-a]pyrimidine (CAS 904817-50-1)
- 1,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 934106-78-2)
- 2-Cyclopropoxy-4-(trifluoromethyl)benzoic acid (CAS 1243473-18-8)
- 4-(5-(Furan-2-yl)-1H-pyrazol-3-yl)piperidine (CAS 111897-11-1)
- (2-(Tert-butoxy)pyridin-4-yl)boronic acid (CAS 2225172-06-3)
- 1-(2-Chloro-6-fluorobenzyl)-1H-imidazole (CAS 108315-13-5)
- 2-(Azetidin-3-yloxy)-N-propylacetamide (CAS 1341137-62-9)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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