2-((4-Fluorophenyl)amino)-2-oxoacetic acid CAS 69066-43-9

Purity 97%+In StockPharmaceutical Standards
CAS No.69066-43-9
Molecular FormulaC8H6FNO3
Molecular Weight183.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-((4-Fluorophenyl)amino)-2-oxoacetic acid CAS 69066-43-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((4-Fluorophenyl)amino)-2-oxoacetic acid.

2-((4-Fluorophenyl)amino)-2-oxoacetic acid (CAS 69066-43-9) is a high-purity analytical reference standard with the molecular formula C8H6FNO3 and a molecular weight of 183.14 g/mol.

Structurally, 2-((4-Fluorophenyl)amino)-2-oxoacetic acid (C8H6FNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 183.14 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H6FNO3
Molecular Weight183.14 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1976
Halogen ContentF-containing
Nitrogen Atoms1

Related Fluorophenyl Standards

Recommended Standards

Why CATO?