trans-4-((tert-Butyldimethylsilyl)oxy)cyclohexanamine CAS 690992-74-6

Purity 97%+In StockPharmaceutical Standards
CAS No.690992-74-6
Molecular FormulaC12H27NOSi
Molecular Weight229.43 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

trans-4-((tert-Butyldimethylsilyl)oxy)cyclohexanamine CAS 690992-74-6 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

trans-4-((tert-Butyldimethylsilyl)oxy)cyclohexanamine (CAS 690992-74-6) is a high-purity analytical reference standard with the molecular formula C12H27NOSi and a molecular weight of 229.43 g/mol.

The molecular framework of trans-4-((tert-Butyldimethylsilyl)oxy)cyclohexanamine (C12H27NOSi) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H27NOSi
Molecular Weight229.43 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)1985
Nitrogen Atoms1

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