5-Amino-2-chloro-4-fluorobenzenesulfonamide CAS 69156-33-8

Purity 97%+In StockPharmaceutical Standards
CAS No.69156-33-8
Molecular FormulaC6H6ClFN2O2S
Molecular Weight224.64 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Amino-2-chloro-4-fluorobenzenesulfonamide CAS 69156-33-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 224.64 g/mol gives 5-Amino-2-chloro-4-fluorobenzenesulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Amino-2-chloro-4-fluorobenzenesulfonamide (CAS 69156-33-8), molecular formula C6H6ClFN2O2S and molecular weight 224.64 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 5-Amino-2-chloro-4-fluorobenzenesulfonamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 224.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Amino-2-chloro-4-fluorobenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H6ClFN2O2S
Molecular Weight224.64 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1976
Halogen ContentF/Cl-containing
Nitrogen Atoms2
Sulfur Atoms1

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