2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carbohydrazide CAS 691868-81-2
| CAS No. | 691868-81-2 |
| Molecular Formula | C13H7F6N5O |
| Molecular Weight | 363.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 363.22 g/mol gives 2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carbohydrazide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carbohydrazide (CAS 691868-81-2), a certified reference material (molecular formula C13H7F6N5O, MW 363.22 g/mol) for analytical method development and quality control.
2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carbohydrazide (C13H7F6N5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carbohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H7F6N5O |
| Molecular Weight | 363.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related bis Standards
- 1-[5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-yl]tetrahydro-4(1H)-pyridinone (CAS 339011-61-9)
- 4-(Trifluoromethyl)-2-[(E)-2-{[3-(trifluoromethyl)phenyl]amino}ethenyl]-1,3-thiazole-5-carbonitrile (CAS 477853-72-8)
- 1-Phenyl-3-[5-(5-(trifluoromethyl)pyridin-2-yl)--[1,2,4]oxadiazol-3-ylmethyl]urea (CAS 1311279-07-8)
- 2-(2-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-1-yl)acetamido)benzoic acid (CAS 672950-89-9)
- 1-[2,6-Bis(trifluoromethyl)quinol-4-yl]homopiperazine (CAS 886761-89-3)
- Methyl 4-{4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}benzenecarboxylate (CAS 321430-12-0)
- 4-Benzyl-1-{[6-(trifluoromethyl)-3-pyridinyl]methyl}-1,4-diazepan-5-one (CAS 909659-37-6)
- 5-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-4,5,6,7-tetrahydro-1H-indol-4-one (CAS 477888-30-5)
Recommended Standards
- (4'-(9H-Carbazol-9-yl)-[1,1'-biphenyl]-4-yl)boronic acid (CAS 858131-73-4)
- Ethyl 2-((1-(2,4-dichloro-5-methoxyphenyl)-1H-tetrazol-5-yl)thio)acetate (CAS 339015-39-3)
- (3-(9-Phenyl-9H-carbazol-3-yl)phenyl)boronic acid (CAS 854952-60-6)
- Fludarabine Phosphate EP Impurity A (CAS 62314-92-5)
- 2-Chloro-4-(piperidine-1-carbonyl)pyridine (CAS 90287-80-2)
- Methyl (2-hydroxybenzyl)glycinate (CAS 182913-11-7)
- 2-(4-Acetyl-6-aminopyridin-2-yl)acetic acid (CAS 1393530-26-1)
- 1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid (CAS 1086423-47-3)
- 2-(4-Fluorophenyl)pyrrolidine (CAS 72216-06-9)
- 4-Methyl-N-((tetrahydro-2H-pyran-4-yl)methyl)pentan-2-amine (CAS 1249249-81-7)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-5-amine (CAS 2020091-14-7)
- 2-(2-Bromopropyl)-5-(trifluoromethyl)pyridine (CAS 1275342-79-4)
- Minocycline Impurity 62 (CAS CATO-C4X-169962)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
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