(E)-6-(4-bromophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2-(3-(trifluoromethyl)phenoxy)ethyl) oxime CAS 691887-91-9
| CAS No. | 691887-91-9 |
| Molecular Formula | C21H15BrF3N3O2S |
| Molecular Weight | 510.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-6-(4-bromophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2-(3-(trifluoromethyl)phenoxy)ethyl) oxime is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(E)-6-(4-bromophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2-(3-(trifluoromethyl)phenoxy)ethyl) oxime (CAS 691887-91-9), molecular formula C21H15BrF3N3O2S and molecular weight 510.33 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-6-(4-bromophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2-(3-(trifluoromethyl)phenoxy)ethyl) oxime (C21H15BrF3N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-6-(4-bromophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2-(3-(trifluoromethyl)phenoxy)ethyl) oxime under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H15BrF3N3O2S |
| Molecular Weight | 510.33 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related E Standards
- 2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-ethoxyphenyl)acetamide (CAS 477330-03-3)
- 2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-ethoxyphenyl)acetamide (CAS 477331-20-7)
- 2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-ethoxyphenyl)acetamide (CAS 477331-53-6)
- 2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxy-5-methylphenyl)acetamide (CAS 477329-62-7)
- 2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-ethoxyphenyl)acetamide (CAS 477329-54-7)
- Ethyl 2-(2-((5-(4-bromophenyl)-1,3,4-oxadiazol-2-yl)thio)propanamido)-4,5-dimethylthiophene-3-carboxylate (CAS 332162-04-6)
- N-(4-Bromophenyl)-3-(N-(4-bromophenyl)sulfamoyl)benzamide (CAS 300670-16-0)
- (Z)-[(4-Bromophenyl)[2-(4-chlorophenyl)cyclopropyl]methylidene][(2,4-dichlorophenyl)methoxy]amine (CAS 338749-09-0)
Recommended Standards
- 4-Bromo-N'-(2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazole-4-carbonyl)benzenesulfonohydrazide (CAS 956961-83-4)
- 3-((2,4-Dichlorobenzyl)sulfonyl)-N-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide (CAS 251097-59-3)
- Avatrombopag Impurity 14 (CAS CATO-C4X-223414)
- 3-((2,6-Dichlorobenzyl)sulfonyl)-N-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide (CAS 251097-54-8)
- Isatin Bis-cresol (CAS 47465-97-4)
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- N5,N5-Dimethylpyrimidine-2,5-diamine (CAS 73418-85-6)
- 2-(4-Cyclohexyl-1,3-thiazol-2-yl)ethan-1-amine dihydrochloride (CAS 1281034-55-6)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
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