Guanosine Impurity 1 CAS 69281-33-0
| CAS No. | 69281-33-0 |
| Molecular Formula | C13H16N7O7P |
| Molecular Weight | 413.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Guanosine Impurity 1 (CAS 69281-33-0) is a certified pharmaceutical impurity reference standard with the molecular formula C13H16N7O7P and a molecular weight of 413.28 g/mol.
The molecular framework of Guanosine Impurity 1 (C13H16N7O7P) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Guanosine Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H16N7O7P |
| Molecular Weight | 413.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 7 |
Related Guanosine Standards
- Guanosine-<SUP>15</SUP>N<SUB>5</SUB>-5′-monophosphate sodium salt (CAS 1257650-86-4)
- Guanosine, N-acetyl-, 2′,3′-diacetate (CAS 65360-02-3)
- Guanosine 5'-Diphosphate (CAS 146-91-8)
- Guanosine Impurity 3 (CAS 117723-13-4)
- Guanosine-5＇-Monophosphate (CAS 85-32-5)
- Guanosine 3',5'-Cyclic Monophosphate (CAS 7665-99-8)
- 160385-87-5 guanosine,8-[(4-chlorophenyl)thio]-, cyclic 3',5'-[(s)-hydrogen phosphorothioate] (9ci) (CAS 160385-87-5)
- Guanosine- (CAS 197228-02-7)
Recommended Standards
- Ethyl 3-((2-amino-5-chlorophenyl)sulfonyl)-5-chloro-1H-indole-2-carboxylate (CAS 206256-33-9)
- 4-((4-(Benzyloxy)-5-bromopyridin-3-yl)sulfonyl)morpholine (CAS 1352532-23-0)
- Delanzomib (CAS 847499-27-8)
- 2-((3-(3,6-Dichloro-9H-carbazol-9-yl)-2-hydroxypropyl)amino)-2-(hydroxymethyl)propane-1,3-diol (CAS 500015-20-3)
- Gaspofungin Impurity F (CAS CATO-C4X-157521)
- Sitagliptin Impurity 24 (CAS CATO-C4X-114424)
- Posaconazole Impurity 117 (CAS CATO-C4X-1208117)
- 8-Fluoro-3,4-dihydro-1h-2-benzothiopyran-4-one (CAS 186424-40-8)
- 2-Amino-N-(2-(trifluoromethoxy)phenyl)acetamide (CAS 1595235-54-3)
- 1,2,7,8-Tetrabromodibenzofuran (CAS 84761-80-8)
- N-(3-Amino-4-chlorophenyl)-3-(isopentyloxy)-benzamide (CAS 1020055-98-4)
- N-Methyl-1-(6-(4-propylpiperazin-1-yl)pyridazin-3-yl)methanamine (CAS 1270720-30-3)
- (4-Fluorophenyl)(pyrrolidin-3-yl)methanone (CAS 26803-29-2)
- Semaglutide Impurity 177 (CAS CATO-C4X-2226177)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com