(2R,3R,4S,5R)-2-(6-Amino-8-ethyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol CAS 69359-47-3
| CAS No. | 69359-47-3 |
| Molecular Formula | C12H17N5O4 |
| Molecular Weight | 295.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 295.29 g/mol gives (2R,3R,4S,5R)-2-(6-Amino-8-ethyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(2R,3R,4S,5R)-2-(6-Amino-8-ethyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 69359-47-3), molecular formula C12H17N5O4 and molecular weight 295.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2R,3R,4S,5R)-2-(6-Amino-8-ethyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (C12H17N5O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2R,3R,4S,5R)-2-(6-Amino-8-ethyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17N5O4 |
| Molecular Weight | 295.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 5 |
Recommended Standards
- (2R,3R,4S,5R)-2-(6-Amino-2,8-dimethyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 63954-66-5)
- (2R,3S,4S,5R)-2-(6-(Dimethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 7770-17-4)
- (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-ethoxy-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 52842-98-5)
- (5-((6,7-Dimethoxybenzo[d][1,3]dioxol-5-yl)methyl)-4,5-dihydroisoxazol-3-yl)methanol (CAS 924871-25-0)
- 5-(4-Amino-3-bromophenyl)-1,3,4-oxadiazole-2-thiol (CAS 887584-46-5)
- 6-Chloro-N-cyclohexyl-N-ethyl-2-pyridinamine (CAS 1220017-75-3)
- propyl 2-cyanopentanoate (CAS CATO-C4X-116658)
- 2-Amino-2-(4-(trifluoromethoxy)phenyl)ethan-1-ol (CAS 942996-03-4)
- Cerestat (CAS 137160-11-3)
- 5-chloro-4-(2-hydroxyethyl)pyridazin-3(2H)-one (CAS 1354455-01-8)
- 1-(3,8-Diazabicyclo[3.2.1]Octan-3-yl)ethan-1-one (CAS 1146852-27-8)
- 2-Cyclopropylpyrimidin-4-ol (CAS 74649-06-2)
- Methyl 1-phenylisoquinoline-3-carboxylate (CAS 1006707-70-5)
- D-Phe6-Tirzepatide (CAS CATO-CPTD788925)
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