(6R,8R,9S,13S,14S,17S)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,6,17-triyl triacetate (Estra-1,3,5(10)-Triene-3,6,17-Triol, Triacetate, (6β,17β) CAS 6944-48-5

Purity 97%+In StockPharmaceutical Standards
CAS No.6944-48-5
Molecular FormulaC24H30O6
Molecular Weight414.49 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(6R,8R,9S,13S,14S,17S)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,6,17-triyl triacetate (Estra-1,3,5(10)-Triene-3,6,17-Triol, Triacetate, (6β,17β) CAS 6944-48-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (6R,8R,9S,13S,14S,17S)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,6,17-triyl triacetate (Estra-1,3,5(10)-Triene-3,6,17-Triol, Triacetate, (6β,17β).

CATO supplies (6R,8R,9S,13S,14S,17S)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,6,17-triyl triacetate (Estra-1,3,5(10)-Triene-3,6,17-Triol, Triacetate, (6β,17β) (CAS 6944-48-5), a certified reference material (molecular formula C24H30O6, MW 414.49 g/mol) for analytical method development and quality control.

The molecular framework of (6R,8R,9S,13S,14S,17S)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,6,17-triyl triacetate (Estra-1,3,5(10)-Triene-3,6,17-Triol, Triacetate, (6β,17β) (C24H30O6) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (6R,8R,9S,13S,14S,17S)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,6,17-triyl triacetate (Estra-1,3,5(10)-Triene-3,6,17-Triol, Triacetate, (6β,17β) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC24H30O6
Molecular Weight414.49 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958

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