3-butyl-2-hydroxyquinazolin-4(3H)-one CAS 6944-59-8
| CAS No. | 6944-59-8 |
| Molecular Formula | C12H14N2O2 |
| Molecular Weight | 218.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-butyl-2-hydroxyquinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-butyl-2-hydroxyquinazolin-4(3H)-one (CAS 6944-59-8), a certified reference material (molecular formula C12H14N2O2, MW 218.25 g/mol) for analytical method development and quality control.
3-butyl-2-hydroxyquinazolin-4(3H)-one (C12H14N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H14N2O2 |
| Molecular Weight | 218.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related butyl Standards
- (E)-3-(4-hydroxyquinazolin-2-yl)acrylic acid (CAS 306996-85-0)
- Methyl 3-(4-hydroxyquinazolin-2-yl)propanoate (CAS 5368-39-8)
- 2-((4-Hydroxyquinazolin-2-yl)thio)acetamide (CAS 16431-31-5)
- 2-[(4-Hydroxyquinazolin-2-yl)sulfanyl]acetic acid (CAS 16431-29-1)
- 2-Ethyl-8-hydroxyquinazolin-4(1H)-one (CAS 105459-51-6)
- 1-(4-Hydroxyquinazolin-3(4H)-yl)ethanone (CAS 94447-50-4)
- 2-(((4-Hydroxyquinazolin-2-yl)methyl)thio)acetic acid (CAS 890647-62-8)
- (4-Hydroxyquinazolin-7-yl)(morpholino)methanone (CAS 1092460-45-1)
Recommended Standards
- 3-Butyl-2-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 94592-93-5)
- 3-Carboethoxyphenyl cyclopropyl ketone (CAS 878745-20-1)
- 3-Benzyl-5,5-dimethylimidazolidine-2,4-dione (CAS 34657-68-6)
- 3-Ethoxy-1-(o-tolyl)-1H-pyrazol-5(4H)-one (CAS 337534-01-7)
- 5-Methyl-2-(morpholinomethyl)-4-oxo-1,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylic acid (CAS 877826-26-1)
- 2,3-Dimethyl-1,1'-biphenyl (CAS 3864-18-4)
- 2-((3,4-Dihydronaphthalen-2-yl)methyl)-4,5-dihydro-1H-imidazole hydrochloride (CAS 87495-33-8)
- 2-(4-Butoxyphenoxy)ethan-1-amine (CAS 893618-52-5)
- 3-Fluoro-4-(piperidin-4-ylmethoxy)pyridine hydrochloride (CAS 2680616-17-3)
- 2,4-Difluorobenzenesulfonamide (CAS 13656-60-5)
- 4-(6-Chloropyridin-2-yl)-3-methylbenzoicacid (CAS 1027511-91-6)
- 4-(3-Methoxypropyl)-5-(4-(morpholinosulfonyl)phenyl)-4H-1,2,4-triazole-3-thiol (CAS 917749-98-5)
- 3-(Aminooxy)propane-1,2-diol (CAS 148322-33-2)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com