Apixaban Impurity N1 CAS 6947-36-0
| CAS No. | 6947-36-0 |
| Molecular Formula | C14H14N2O3 |
| Molecular Weight | 258.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Apixaban Impurity N1 (CAS 6947-36-0) is a certified pharmaceutical impurity reference standard with the molecular formula C14H14N2O3 and a molecular weight of 258.27 g/mol.
Based on its molecular formula C14H14N2O3, Apixaban Impurity N1 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 258.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Apixaban Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14N2O3 |
| Molecular Weight | 258.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Apixaban Standards
- Apixaban Impurity 99 (CAS 22715-73-7)
- Apixaban Impurity 81 (CAS CATO-C4X-108881)
- Apixaban Impurity 110 (CAS 473927-63-8)
- Apixaban Impurity 14 (CAS 405872-78-8/2228998-99-8)
- Apixaban Impurity 18 (CAS 27143-07-3)
- Apixaban Impurity 36 (CAS 85014-68-2/2228050-22-2)
- Apixaban Impurity 64 (CAS 1039914-85-6)
- Apixaban Impurity 178 (CAS 1579955-59-1)
Recommended Standards
- 8-Acetyl-7-hydroxy-6-methyl-2,3-dihydrocyclopenta[c]chromen-4(1h)-one (CAS 951626-57-6)
- Benzo[1,2-b;4,5-b']bisbenzofuran" (CAS 208-37-7)
- 8-(Ethoxycarbonyl)-1,4-dioxaspiro[4.5]Decane-8-carboxylic acid (CAS 2375192-30-4)
- Benzo[2,1-b:3,4-b']bisbenzofuran (CAS 222-23-1)
- Epinephrine Impurity 114 (CAS CATO-C4X-1849114)
- Tirofiban Impurity 77 (CAS 13022-41-8)
- Fluticasone Propionate EP Impurity H (CAS 201812-64-8)
- 5-Aminopyridine-3-sulfonic acid (CAS 62009-35-2)
- n'-Hydroxy-2-[(3-methoxyphenyl)methoxy]ethanimidamide (CAS 1016864-21-3)
- 2,5-Dimethyl-N-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)furan-3-carboxamide (CAS 1203145-54-3)
- TranS,trans-1,4-diacetoxy-1,3-butadiene (CAS 15910-11-9)
- 4-Cyclopropoxy-6-methoxypyridine-3-sulfonamide (CAS 1243465-82-8)
- 6-Hydrazinylbenzofuran-2-carboxylic acid (CAS 76897-54-6)
- Acetyl decapeptide-3 (CAS 935288-50-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com