5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylfuran-3-carboxylic acid CAS 696649-78-2
| CAS No. | 696649-78-2 |
| Molecular Formula | C14H12O5 |
| Molecular Weight | 260.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylfuran-3-carboxylic acid (CAS 696649-78-2) is a high-purity analytical reference standard with the molecular formula C14H12O5 and a molecular weight of 260.24 g/mol.
The molecular framework of 5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylfuran-3-carboxylic acid (C14H12O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12O5 |
| Molecular Weight | 260.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
Related Dihydrobenzo Standards
- 3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 1177272-78-4)
- 1-(1,5-Dihydrobenzo[e][1,3]dioxepin-3-yl)-N-(furan-2-ylmethyl)methanamine (CAS 374913-99-2)
- n-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1h-imidazole-1-carboxamide (CAS 1087784-59-5)
- 5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)isoxazole-3-carbohydrazide (CAS 763109-45-1)
- Methyl 5-(2,3-dihydrobenzo[b][1,4]dioxin-7-yl)isoxazole-3-carboxylate (CAS 925004-56-4)
- N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)thiophene-2-carboxamide (CAS 288312-08-3)
- N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)thiophene-3-carboxamide (CAS 923734-91-2)
- N-((1,5-dihydrobenzo[e][1,3]dioxepin-3-yl)methyl)cyclohexanamine (CAS 332167-80-3)
Recommended Standards
- 5-((4-Acetylphenoxy)methyl)furan-2-carboxylic acid (CAS 832740-35-9)
- 5,6-Dihydro-5-methyluridine (CAS 23067-10-9)
- 4-Amino-3-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 537050-10-5)
- 6-[(3,4,4-Trifluorobut-3-en-1-yl)sulfanyl]-9H-purine (CAS 478067-83-3)
- tert-Butyl Iodoacetate (CAS 49827-15-8)
- 2-Chloro-4-(difluoromethyl)-5-hydroxynicotinonitrile (CAS 1806915-01-4)
- 7-Benzyl-4-chloro-5,6-dimethyl-7h-pyrrolo[2,3-d]pyrimidine (CAS 173458-80-5)
- (1-(5-Bromopyrimidin-2-yl)piperidin-3-yl)methanol (CAS 1189973-29-2)
- 2,9-Dithiadecane (CAS 56348-40-4)
- 4-Bromo-6-fluoro-2-(hydroxymethyl)benzimidazole (CAS 1935913-37-3)
- N,N-Dimethylbenzylamine (CAS 103-83-3)
- 4-Ethyl-5-methoxy-1H-imidazole (CAS 239124-60-8)
- N-(3,4-Dimethylisoxazol-5-yl)-N-((2-methoxyethoxy)methyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide (CAS 176961-13-0)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
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