2,2-Difluoro-3-Methylenecyclobutanecarboxylic Acid CAS 697-55-2
| CAS No. | 697-55-2 |
| Molecular Formula | C6H6F2O2 |
| Molecular Weight | 148.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,2-Difluoro-3-Methylenecyclobutanecarboxylic Acid (CAS 697-55-2) is a high-purity analytical reference standard with the molecular formula C6H6F2O2 and a molecular weight of 148.11 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 2,2-Difluoro-3-Methylenecyclobutanecarboxylic Acid is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 148.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6F2O2 |
| Molecular Weight | 148.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
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